Conjugational synthesis of F lac + and Col I DNA in the presence of Rifampicin and in Escherichia coli K12 mutants defective in DNA synthesis

1974 ◽  
Vol 134 (2) ◽  
pp. 143-156 ◽  
Author(s):  
Brian M. Wilkins ◽  
Susan E. Hollom
Keyword(s):  
Escherichia Coli ◽  
Dna Synthesis ◽  
Escherichia Coli K12

Inhibitors of DNA synthesis cause excessive DNA synthesis in dnaA mutants of Escherichia coli K12

1978 ◽  
Vol 24 (10) ◽  
pp. 1250-1252
Author(s):  
Jukka Heinonen ◽  
Marja-Leena Pekola
Keyword(s):  
Escherichia Coli ◽  
Dna Synthesis ◽  
Relative Rate ◽  
Cell Mass ◽  
Chromosomal Dna ◽  
E Coli ◽  
Escherichia Coli K12 ◽  
Low Concentrations ◽  
Dna Synthesis Inhibitors

The relative rate of net DNA synthesis was stimulated when cells of dnaA mutants of Escherichia coli K12 were grown in the presence of low concentrations of DNA synthesis inhibitors. This led to a supernormal DNA/cell mass ratio. The excessive DNA was similar to the normal chromosomal DNA in size and stability in vivo. However, the cells did not divide but turned into long filaments. Excessive DNA synthesis in the presence of inhibitors of DNA synthesis was observed in the cultures of two independent dnaA mutants of E. coli, but dnaB and dnaC mutants behaved like the wild type in this respect.

Mutations that alter the pore function of the ompF porin of Escherichia coli K12

1988 ◽  
Vol 203 (4) ◽  
pp. 961-970 ◽  
Author(s):  
S.A. Benson ◽  
J.L.L. Occi ◽  
B.A. Sampson
Keyword(s):  
Escherichia Coli ◽  
Ompf Porin ◽  
Escherichia Coli K12
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