A new mutation for multiple drug resistance and modified plasma membrane ATPase activity in Schizosaccharomyces pombe

1986 ◽  
Vol 10 (5) ◽  
pp. 359-364 ◽  
Author(s):  
Stanislaw Ulaszewski ◽  
Alan Coddington ◽  
Andr� Goffeau
Keyword(s):  
Drug Resistance ◽  
Plasma Membrane ◽  
Atpase Activity ◽  
Schizosaccharomyces Pombe ◽  
Multiple Drug Resistance ◽  
Multiple Drug ◽  
Plasma Membrane Atpase ◽  
New Mutation ◽  
Membrane Atpase

scholarly journals Interactions between the gene products of pma1 encoding plasma membrane H(+)-ATPase, and pdr1 controlling multiple drug resistance in Saccharomyces cerevisiae.

1993 ◽  
Vol 40 (4) ◽  
pp. 487-496 ◽  
Author(s):  
S Ułaszewski
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Drug Resistance ◽  
Plasma Membrane ◽  
Atpase Activity ◽  
Multiple Drug Resistance ◽  
Multidrug Resistant ◽  
Multiple Drug ◽  
Gene Products ◽  
In Trans

In Saccharomyces cerevisiae, the pma1 mutations controlling the vanadate resistance of the H(+)-ATPase activity from the plasma membrane, map on chromosome VII in the vicinity of pdr1 mutations controlling multiple drug resistance. However, the pma1-1 mutants exhibit a genotype and a multidrug resistant phenotype quite different from those obtained for pdr1 mutants. Quantitative modifications of cycloheximide and N,N'-(p-xylylidene)-bis-aminoguanidine-2HCl resistance are observed in diploids containing the pma1 and pdr1 genes in trans configuration. Each of the pdr1 mutations interacts with pma1 as shown by a decrease in the ATPase activity in pdr1/pma1 diploids. The in vitro resistance of ATPase activity to vanadate is totally or partially suppressed in pdr1 mutants in haploid double mutants. These results suggest that the expression of PMA1 might be controlled by the PDR1 gene product.

Change in plasma membrane ATPase activity during dormancy release of vegetative peach-tree buds

1999 ◽  
Vol 106 (1) ◽  
pp. 41-46 ◽  
Author(s):  
Henri-Luc Aue ◽  
Isabelle Lecomte ◽  
Michel Gendraud ◽  
Gilles Pétel
Keyword(s):  
Plasma Membrane ◽  
Atpase Activity ◽  
Dormancy Release ◽  
Peach Tree ◽  
Plasma Membrane Atpase ◽  
Membrane Atpase

Direct Action of Insulin on Plasma Membrane ATPase Activity in Human Lymphocytes

1972 ◽  
Vol 235 (58) ◽  
pp. 174-177 ◽  
Author(s):  
JOHN W. HADDEN ◽  
ELBA M. HADDEN ◽  
EDWIN E. WILSON ◽  
ROBERT A. GOOD ◽  
RONALD G. COFFEY
Keyword(s):  
Plasma Membrane ◽  
Atpase Activity ◽  
Direct Action ◽  
Human Lymphocytes ◽  
Plasma Membrane Atpase ◽  
Membrane Atpase
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