Alterations in morphine analgesia produced by chronic deficits of brain catecholamines or serotonin: Role of analgesimetric procedure

1978 ◽  
Vol 56 (2) ◽  
pp. 119-125 ◽  
Author(s):  
James L. York ◽  
E. W. Maynert
Keyword(s):  
Morphine Analgesia ◽  
Brain Catecholamines

Role of spinal 5-HT1A receptors in morphine analgesia and tolerance in rats

2004 ◽  
Vol 8 (3) ◽  
pp. 253-261 ◽  
Author(s):  
Laurent Bardin ◽  
Francis C. Colpaert
Keyword(s):  
Morphine Analgesia

Antidepressants in Cancer Pain

1991 ◽  
Vol 7 (4) ◽  
pp. 42-44 ◽  
Author(s):  
Alberto E. Panerai ◽  
Mauro Bianchi ◽  
Paola Sacerdote ◽  
Carla Ripamonti ◽  
Vittorio Ventafridda ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Cancer Pain ◽  
Beneficial Effect ◽  
Nerve Injury ◽  
Analgesic Effect ◽  
Tricyclic Antidepressants ◽  
Antidepressant Drugs ◽  
Depressive Illness ◽  
Morphine Analgesia

Studies conducted in recent years have helped define the role of antidepressant drugs in the management of cancer pain. The anti-nociceptive action of these agents seems to be independent of beneficial effect on depression or mood. Among antidepressant drugs, those of the tricyclic class are preferred when an analgesic effect is sought. Their primary application is for pain due to nerve injury, so-called “neuropathic pain”. Although the co-administration of tricyclic antidepressants may increase plasma morphine concentrations, any potentiation of morphine analgesia is thought not to be due to an increased bioavailability of the opiate, but to an intrinsic analgesic effect of antidepressants. On this basis, the use of antidepressants in combination with opioids for the treatment of cancer pain is suitable when a component of deafferentation is present or when there is concomitant depressive illness.

scholarly journals The Role of the Paraventricular Nucleus and Pituitary Gland in Morphine Analgesia

1991 ◽  
Vol 31 (10) ◽  
pp. 629-634 ◽  
Author(s):  
Masaaki HASHIMOTO ◽  
Shoichiro OHGAMI ◽  
Yukichi YONEMASU
Keyword(s):  
Pituitary Gland ◽  
Paraventricular Nucleus ◽  
Morphine Analgesia

P.6.d.005 Evaluation of the role of central adenosine A1 and A2a receptors in the development of tolerance to morphine analgesia in rats

2010 ◽  
Vol 20 ◽  
pp. S590-S591
Author(s):  
M. Charkhpour ◽  
A. Parvizpur ◽  
F. Ebrahimi ◽  
P. Talebi ◽  
H. Samadi ◽  
...  
Keyword(s):  
Morphine Analgesia ◽  
A2a Receptors ◽  
Adenosine A1 ◽  
Development Of Tolerance

The role of brain catecholamines in the exhibition of muricide induced by nucleus accumbens lesions and the effect of antidepressants in rats

1987 ◽  
Vol 26 (2) ◽  
pp. 351-355 ◽  
Author(s):  
Izaldin M.H. Al-Khatib ◽  
Michihiro Fujiwara ◽  
Katsunori Iwasaki ◽  
Yasufumi Kataoka ◽  
Showa Ueki
Keyword(s):  
Nucleus Accumbens ◽  
Brain Catecholamines
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