Effects of cyclopiazonic acid and aflatoxin singly and in combination on selected clinical, pathological and immunological responses of guinea pigs

1989 ◽  
Vol 105 (3) ◽  
pp. 135-142 ◽  
Author(s):  
A. C. Pier ◽  
E. L. Belden ◽  
J. A. Ellis ◽  
E. W. Nelson ◽  
L. R. Maki
1993 ◽  
Vol 21 (1) ◽  
pp. 31-37 ◽  
Author(s):  
HARRY L. RITZ ◽  
BETTIE L. B. EVANS ◽  
ROBERT D. BRUCE ◽  
E. ROBERT FLETCHER ◽  
GERALD L. FISHER ◽  
...  

1974 ◽  
Vol 4 (1) ◽  
pp. 60-62 ◽  
Author(s):  
Vanda A. Lennon ◽  
P. R. Carnegie

1988 ◽  
Vol 59 (1) ◽  
pp. 149-154 ◽  
Author(s):  
P. C. Verma ◽  
R. P. Gupta ◽  
J. R. Sadana ◽  
R. K. Paul Gupta

1. Cellular and humoral immune responses were studied in guinea-pigs fed on zinc-deficient (ZnD), Zn-adequate (control) and Zn-replete diets containing 1·25, 50 and 100 mg Zn/kg diet respectively.2. It was found that the ZnD guinea-pigs had significantly decreased ability to elicit delayed-type hypersensitivity (DTH) response against sheep erythrocytes as compared with controls on the 9th day of immunization. This was further substantiated by histological examination of DTH-positive skin sections.3. A significant reduction in direct splenic plaque-forming-cell response and haemagglutinating-antibody titre was also observed in ZnD guinea-pigs.4. Serum electrophoretic studies revealed a highly disordered protein profile with a significantly depressed value for γ-globulin.5. Zn repletion of the previously ZnD group resulted in marked, though incomplete, restoration of immunological responses.


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