Secretion of monoquaternary ammonium compounds by guinea pig small intestine in vivo

1977 ◽  
Vol 299 (3) ◽  
pp. 201-205 ◽  
Author(s):  
Klaus Turnheim ◽  
Fritz Lauterbach
Keyword(s):  
Small Intestine ◽  
Guinea Pig ◽  
Monoquaternary Ammonium ◽  
Ammonium Compounds

Trans-Mucosal Passage of Intact Peptides in the Guinea-Pig Small Intestine in Vivo: A Re-Appraisal

1983 ◽  
Vol 64 (4) ◽  
pp. 433-439 ◽  
Author(s):  
Michael L. G. Gardner ◽  
Bo S. Lindblad ◽  
David Burston ◽  
David M. Matthews
Keyword(s):  
Amino Acids ◽  
Small Intestine ◽  
Chemical Analysis ◽  
Guinea Pig ◽  
Venous Blood ◽  
Amino Nitrogen ◽  
Confidence Limits ◽  
Small Peptides ◽  
Intraduodenal Infusion

1. Re-examination of data for the chemical analysis of peptide-bound amino acids in the mesenteric venous blood of anaesthetized guinea-pigs suggests that there are small, but significant, amounts of small peptides in the blood of fasted animals. 2. Furthermore, there is a significant increase in the peptide content of the mesenteric venous blood during intraduodenal infusion of a partial digest of casein. 3. The data are consistent with the view that some 10% of the amino nitrogen entering the mesenteric blood during absorption of a casein digest in vivo may be in the form of small peptides, although it is not possible to define confidence limits for this estimate.

Secretion of electrolytes and water by the guinea pig small intestine in vivo

1968 ◽  
Vol 215 (5) ◽  
pp. 1226-1233 ◽  
Author(s):  
DW Powell ◽  
SJ Malawer ◽  
GR Plotkin
Keyword(s):  
Small Intestine ◽  
Guinea Pig

Absorption of bile salts from the small intestine in vivo

1962 ◽  
Vol 202 (1) ◽  
pp. 155-157 ◽  
Author(s):  
I. M. Weiner ◽  
Leon Lack
Keyword(s):  
Small Intestine ◽  
Small Bowel ◽  
Guinea Pig ◽  
Biliary Excretion ◽  
High Fat Diet ◽  
Bile Salts ◽  
Distal Part ◽  
High Fat

The absorption of bile salts from the small intestine of the guinea pig was studied in vivo by determining the biliary excretion of bile salts injected into isolated regions of the small bowel Taurocholate, glycocholate, and cholate appeared in bile in significant amounts only when they were introduced into the distal part of the small intestine (ileum), indicating that there is little, if any, absorption by diffusion through the proximal mucosa. Allowing animals to eat a relatively high fat diet before the experiments did not alter the pattern of intestinal absorption of bile salts. The results confirm previous in vitro studies on the active transport of bile salts by the ileum.

The uptake of lead by small intestine, colon and gallbladder of the guinea pig in vivo

1984 ◽  
Vol 81 (6) ◽  
pp. 591-596 ◽  
Author(s):  
K. A. Hussein ◽  
S. B. Coghill ◽  
G. Milne ◽  
D. Hopwood
Keyword(s):  
Small Intestine ◽  
Guinea Pig

Immunochemical visualization of cyclic AMP in myenteric neurons of guinea-pig small intestine+

2001 ◽  
Vol 120 (5) ◽  
pp. A683-A683
Author(s):  
J GUZMAN ◽  
S SHARP ◽  
J YU ◽  
F MCMORRIS ◽  
A WIEMELT ◽  
...  
Keyword(s):  
Small Intestine ◽  
Cyclic Amp ◽  
Guinea Pig ◽  
Myenteric Neurons

Effects of stimulating protease-activated receptors on myenteric newrons in guinea-pig small intestine

2001 ◽  
Vol 120 (5) ◽  
pp. A114-A114
Author(s):  
C GAO ◽  
H HU ◽  
S LIU ◽  
N GAO ◽  
Y XIA ◽  
...  
Keyword(s):  
Small Intestine ◽  
Guinea Pig ◽  
Protease Activated Receptors

Inhibition of Human and Animal Platelet Adhesiveness to Glass Bead Columns by Adenosine, Dipyridamole, Chlorpromazine and Acetylsalicylic Acid

1976 ◽  
Vol 36 (02) ◽  
pp. 401-410 ◽  
Author(s):  
Buichi Fujttani ◽  
Toshimichi Tsuboi ◽  
Kazuko Takeno ◽  
Kouichi Yoshida ◽  
Masanao Shimizu
Keyword(s):  
Guinea Pig ◽  
Acetylsalicylic Acid ◽  
Guinea Pigs ◽  
Glass Bead ◽  
Animal Species ◽  
Inhibitory Effect ◽  
Rabbit Platelet ◽  
Platelet Adhesiveness

SummaryThe differences among human, rabbit and guinea-pig platelet adhesiveness as for inhibitions by adenosine, dipyridamole, chlorpromazine and acetylsalicylic acid are described, and the influence of measurement conditions on platelet adhesiveness is also reported. Platelet adhesiveness of human and animal species decreased with an increase of heparin concentrations and an increase of flow rate of blood passing through a glass bead column. Human and rabbit platelet adhesiveness was inhibited in vitro by adenosine, dipyridamole and chlorpromazine, but not by acetylsalicylic acid. On the other hand, guinea-pig platelet adhesiveness was inhibited by the four drugs including acetylsalicylic acid. In in vivo study, adenosine, dipyridamole and chlorpromazine inhibited platelet adhesiveness in rabbits and guinea-pigs. Acetylsalicylic acid showed the inhibitory effect in guinea-pigs, but not in rabbits.

In vivo activity of pyrimidine-dispirotripiperaziniumin in the male guinea pig model of genital herpes

2020 ◽  
Vol 09 (01) ◽  
Author(s):  
Novoselova EA ◽  
Alimbarova LM ◽  
Monakhova NS ◽  
Lepioshkin AY ◽  
Ekins S ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Genital Herpes ◽  
Pig Model ◽  
Guinea Pig Model

scholarly journals Optimization of spectral-domain optical coherence tomography with a supercontinuum source for in vivo motion detection of low reflective outer hair cells in guinea pig cochleae

2021 ◽  
Author(s):  
Fumiaki Nin ◽  
Samuel Choi ◽  
Takeru Ota ◽  
Zhang Qi ◽  
Hiroshi Hibino
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Guinea Pig ◽  
Hair Cells ◽  
Sensory Epithelium ◽  
Outer Hair Cells ◽  
Acquisition Time ◽  
Total Acquisition Time ◽  
Sd Oct

AbstractSound evokes sub-nanoscale vibration within the sensory epithelium. The epithelium contains not only immotile cells but also contractile outer hair cells (OHCs) that actively shrink and elongate synchronously with the sound. However, the in vivo motion of OHCs has remained undetermined. The aim of this work is to perform high-resolution and -accuracy vibrometry in live guinea pigs with an SC-introduced spectral-domain optical coherence tomography system (SD-OCT). In this study, to reveal the effective contribution of SC source in the recording of the low reflective materials with the short total acquisition time, we compare the performances of the SC-introduced SD-OCT (SCSD-OCT) to that of the conventional SD-OCT. As inanimate comparison objects, we record a mirror, a piezo actuator, and glass windows. For the measurements in biological materials, we use in/ex vivo guinea pig cochleae. Our study achieved the optimization of a SD-OCT system for high-resolution in vivo vibrometry in the cochlear sensory epithelium, termed the organ of Corti, in mammalian cochlea. By introducing a supercontinuum (SC) light source and reducing the total acquisition time, we improve the axial resolution and overcome the difficulty in recording the low reflective material in the presence of biological noise. The high power of the SC source enables the system to achieve a spatial resolution of 1.72 ± 0.00 μm on a mirror and reducing the total acquisition time contributes to the high spatial accuracy of sub-nanoscale vibrometry. Our findings reveal the vibrations at the apical/basal region of OHCs and the extracellular matrix, basilar membrane.

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