Ontogenesis of neostriatal cholinergic neurones in the rat and development of their sensitivity to neuroleptic drugs

1975 ◽  
Vol 288 (2-3) ◽  
pp. 329-334 ◽  
Author(s):  
P. G. Guyenet ◽  
J. C. Beaujouan ◽  
J. Glowinski
Keyword(s):  
Neuroleptic Drugs ◽  
Cholinergic Neurones

359 Cardiac lesions induced by neuroleptic drugs in the rabbit

2006 ◽  
Vol 5 (1) ◽  
pp. 78-78
Author(s):  
D BELHANI ◽  
D FRASSATI ◽  
R MEGARD ◽  
Q TIMOURCHAH ◽  
B BUIXUAN ◽  
...  
Keyword(s):  
Neuroleptic Drugs ◽  
Cardiac Lesions

Prolactin and Neuroleptic Drugs

1988 ◽  
Vol 6 (1) ◽  
pp. 213-223 ◽  
Author(s):  
Alan I. Green ◽  
Walter A. Brown
Keyword(s):  
Neuroleptic Drugs

The Lifetime Outcome and Involuntary Movements of Schizophrenia Never Treated with Neuroleptic Drugs

1990 ◽  
Vol 156 (1) ◽  
pp. 106-108 ◽  
Author(s):  
John L. Waddington ◽  
Hanafy A. Youssef
Keyword(s):  
Cognitive Dysfunction ◽  
Clinical Characteristics ◽  
Neuroleptic Drugs ◽  
Involuntary Movements ◽  
Orofacial Movements ◽  
Schizophrenic Patients

Four elderly schizophrenic patients who had never been treated with neuroleptics, and a fifth patient who had received only the briefest exposure to such drugs, had retained their distinct clinical characteristics. Involuntary orofacial movements and cognitive dysfunction were found more uniformly than any particular pattern of symptoms.

Regional selectivity of neuroleptic drugs: An argument for site specificity

1983 ◽  
Vol 11 (2) ◽  
pp. 215-218 ◽  
Author(s):  
Richard L. Borison ◽  
Bruce I. Diamond
Keyword(s):  
Site Specificity ◽  
Neuroleptic Drugs ◽  
Regional Selectivity

Persistence of Neurological Symptoms Due to Neuroleptic Drugs

1971 ◽  
Vol 127 (10) ◽  
pp. 1407-1410 ◽  
Author(s):  
GEORGE E. CRANE
Keyword(s):  
Neurological Symptoms ◽  
Neuroleptic Drugs

Effect of Ageing on Post-Lesion Oestradiol Treatment on Mouse Cholinergic Neurones In Vivo

2012 ◽  
Vol 24 (9) ◽  
pp. 1243-1248 ◽  
Author(s):  
Z. Kőszegi ◽  
I. M. Ábrahám
Keyword(s):  
Oestradiol Treatment ◽  
Cholinergic Neurones

Patients' awareness of extrapyramidal reactions to neuroleptic drugs: Possible evidence for the role of catecholamines in perception

1979 ◽  
Vol 1 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Robert Freedman ◽  
Morton M. Silverman ◽  
Paul J. Schwab
Keyword(s):  
Neuroleptic Drugs

Treatment of tardive dyskinesia

1978 ◽  
Vol 16 (14) ◽  
pp. 55-56
Keyword(s):  
Tardive Dyskinesia ◽  
Late Onset ◽  
Psychiatric Patients ◽  
Term Treatment ◽  
Neuroleptic Drugs ◽  
Abnormal Movements ◽  
Long Term Treatment ◽  
The Face ◽  
Schizophrenic Patients

Neuroleptic drugs cause many forms of extra-pyramidal syndromes. One of these, tardive dyskinesia,1 occurs only after the patient has been taking the drug for some time (‘tardive’ refers to the late onset). The movements are involuntary and repetitive usually involving the face and tongue, but they may also affect the limbs and trunk. Tongue protrusion, licking and smacking of the lips, sucking and chewing movements, grimacing, grunting, blinking and furrowing of the forehead have all been described and attributed to long-continued medication with neuroleptic drugs of the phenothiazine, butyrophenone and thioxanthene groups. The patient can inhibit the movements, but anxiety makes them worse. Many of these symptoms were noticed in schizophrenic patients before neuroleptic drugs were introduced2 and they can occur in otherwise normal untreated elderly people. Nevertheless it is generally accepted that in most cases tardive dyskinesia is an unwanted effect of neuroleptic medication. Despite suggestions to the contrary, the abnormal movements are not necessarily associated with high dosage of neuroleptic drugs or with pre-existing brain damage.3 4 Tardive dyskinesia has been reported in 3–6% of a mixed population of psychiatric patients5 and over half of a group of chronic schizophrenics on long-term treatment.4 The more careful the neurological examination, the greater the apparent incidence.

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