Effects of carbon monoxide or low oxygen gas mixture inhalation on regional oxygenation, blood flow, and small vessel blood content of the rabbit heart

1980 ◽  
Vol 383 (2) ◽  
pp. 105-111 ◽  
Author(s):  
Hollis D. Kleinert ◽  
James L. Scales ◽  
Harvey R. Weiss
1957 ◽  
Vol 191 (3) ◽  
pp. 446-452 ◽  
Author(s):  
Hans G. Borst ◽  
James L. Whittenberger ◽  
Erik Berglund ◽  
Maurice McGregor

Effects of hypoxia and of hypercapnia on pulmonary blood flow distribution were examined in 19 dogs. The blood flow through each lung was continuously recorded; the test gas was administered to one lung, and the other lung was used as the control. Low oxygen gas mixtures were administered to one lung for periods of 2–47 minutes. When constriction occurred, it began within one-half minute after the gas administration was started and reached a plateau within 8–20 minutes. Vasodilation was never observed. In most animals no vasomotor effect of hypoxia was found early in the experiment (less than 6 hr. after induction of anesthesia), but seven of the early nonreactors became positive later in the experiment. After 6–8 hours from induction of anesthesia, all animals tested showed a vasoconstrictor response to hypoxia. The administration to one lung of 5 or 10% carbon dioxide for 2–10 minutes was always accompanied by vasoconstriction in that lung. In dogs that showed unilateral pulmonary vasoconstriction during hypoxia, further vasoconstriction was produced by adding 5% carbon dioxide. Some of the contradictory results of other investigators may be explained by the refractory period observed in these experiments.


2015 ◽  
Vol 86 (1) ◽  
pp. 15-20
Author(s):  
Xiaopeng Liu ◽  
Huajun Xiao ◽  
Weiru Shi ◽  
Dongqing Wen ◽  
Lihua Yu ◽  
...  

BIOPHYSICS ◽  
2020 ◽  
Vol 65 (4) ◽  
pp. 666-675
Author(s):  
E. E. Fesenko ◽  
E. L. Gagarinsky ◽  
A. S. Averin ◽  
N. V. Grudinin ◽  
A. E. Gurin ◽  
...  

2018 ◽  
Author(s):  
Xiaofeng Yang ◽  
Yewei Gui ◽  
Wei Tang ◽  
Yanxia Du ◽  
Guangming Xiao ◽  
...  

2020 ◽  
Vol 28 (6) ◽  
pp. 1566-1581
Author(s):  
Bahador Akbari ◽  
Asghar Lashanizadegan ◽  
Parviz Darvishi ◽  
Abdolrasoul Pouranfard
Keyword(s):  

1988 ◽  
Vol 69 (3A) ◽  
pp. A216-A216 ◽  
Author(s):  
J. F. Baron ◽  
E. Vicaut ◽  
X. HOU ◽  
P. Vlars ◽  
M. Duvelleroy

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