Physiological Effects of Positive Pressure Breathing with Pure Oxygen and a Low Oxygen Gas Mixture

2015 ◽  
Vol 86 (1) ◽  
pp. 15-20
Author(s):  
Xiaopeng Liu ◽  
Huajun Xiao ◽  
Weiru Shi ◽  
Dongqing Wen ◽  
Lihua Yu ◽  
...  
2018 ◽  
Author(s):  
Xiaofeng Yang ◽  
Yewei Gui ◽  
Wei Tang ◽  
Yanxia Du ◽  
Guangming Xiao ◽  
...  

2020 ◽  
Vol 28 (6) ◽  
pp. 1566-1581
Author(s):  
Bahador Akbari ◽  
Asghar Lashanizadegan ◽  
Parviz Darvishi ◽  
Abdolrasoul Pouranfard
Keyword(s):  

Author(s):  
Carl Waldmann ◽  
Andrew Rhodes ◽  
Neil Soni ◽  
Jonathan Handy

This chapter discusses respiratory drugs and includes discussion on bronchodilators (describing β‎2-agonists, anticholinergic agents, and xanthine derivatives), nitric oxide (history, biochemistry, clinical use of inhaled nitric oxide, administration of inhaled nitric oxide, adverse effects of inhaled nitric oxide, and adjunctive therapies), mucolytics (properties of mucus, types of mucolytics, clinical applications, and side-effects), and helium–oxygen gas mixtures (including nomenclature, rationale, indications, expected effects, presentation, face mask administration, nebulization, patient monitoring during therapy, stopping helium–oxygen therapy, indications for helium–oxygen mask ventilation, indications for helium–oxygen intermittent positive pressure ventilation (IPPV) via endotracheal or tracheostomy tube, patient monitoring during IPPV therapy, stopping helium–oxygen therapy, and published trials).


1993 ◽  
Vol 264 (2) ◽  
pp. H484-H489 ◽  
Author(s):  
J. Haynes ◽  
A. E. Taylor ◽  
D. Dixon ◽  
N. Voelkel

In this study the effects of alveolar hypoxia on pulmonary microvascular hemodynamics in sickle red blood cell (HbSS-RBC) perfused rat lungs were studied under conditions of high and low oxygen tensions and compared with lung perfused with rat (HbRat) and normal human (HbAA) RBC controls. Independent of the RBC suspension (hematocrit 5%) used, ventilation with the room air gas mixture did not result in any significant differences in the pulmonary arterial pressure (Ppa), capillary pressure (Ppc), total pulmonary vascular resistance (RT), or angiotensin II pressor response. Ventilation of HbSS-RBC perfused lungs with a hypoxic gas mixture significantly increased the Ppa, Ppc, and RT above that which was seen in HbRat and HbAA controls. The increase in RT occurred mainly in the pulmonary artery independent of RBC suspension. In addition, no significant accumulation of lung water occurred in HbSS-RBC perfused lungs compared with HbRat and HbAA controls, as indicated by the change in capillary filtration coefficient and wet-to-dry lung weight ratio. In conclusion, deoxygenation of the HbSS-RBC and hypoxic pulmonary vasoconstriction is additive in altering pulmonary microvascular hemodynamics.


1996 ◽  
Vol 438 ◽  
Author(s):  
Y. Cheong ◽  
H. Du ◽  
S. P. Withrow

AbstractThe role of aluminum in negating the adverse effect of alkali species on the oxidation resistance of Si3N4 ceramics was investigated by exposing unimplanted and aluminum-implanted (1 and 5 at.%) Si3N4 samples to a sodium nitrate (95 ppm)-dry oxygen gas mixture at 1. atm and at 900°1100°C. Oxidation of unimplanted Si3N4 was rapid and linear with an activation energy of 57 kJ/mol. In contrast, samples implanted with aluminum exhibited a considerably reduced oxide growth which was parabolic in nature with activation energies of 103–112 kJ/mol. The morphological characteristics of the oxide layer also showed marked improvement as the aluminum concentration increased.


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