Cerebellar histogenesis and synaptic maturation following pre- and postnatal alcohol administration

1984 ◽  
Vol 63 (1) ◽  
pp. 57-65 ◽  
Author(s):  
B. Volk
Keyword(s):  
Alcohol Administration ◽  
Synaptic Maturation ◽  
Cerebellar Histogenesis

THE INFLUENCE OF VITAMIN C ON EOSINOPHIL RESPONSE TO ACUTE ALCOHOL INTOXICATION IN RATS

1960 ◽  
Vol XXXV (IV) ◽  
pp. 585-593 ◽  
Author(s):  
T. P. J. Vanha-Perttula
Keyword(s):  
Vitamin C ◽  
Ethyl Alcohol ◽  
Intraperitoneal Injection ◽  
Alcohol Intoxication ◽  
Albino Rats ◽  
Acute Alcohol Intoxication ◽  
Alcohol Administration ◽  
Initial Values

ABSTRACT The effect of ethyl alcohol on the circulating eosinophil cells has been studied in female albino rats. An intoxicating dose of alcohol caused a marked depletion of circulating eosinophils which was most clearly evident four hours after the administration of the alcohol. The initial values were not reached before 24 hours had elapsed. Intraperitoneal injection of vitamin C 12 hours prior to the alcohol administration very effectively prevented this eosinopenic reaction. The mechanism of regulation of the eosinophil cells in the circulation has been discussed in the light of previous results and of those obtained in this study.

scholarly journals Acupuncture Alleviates Anxiety and 22-kHz Ultrasonic Vocalizations in Rats Subjected to Repeated Alcohol Administration by Modulating the Brain-Derived Neurotrophic Factor/Corticotropin-Releasing Hormone Signaling Pathway

2021 ◽  
Vol 22 (8) ◽  
pp. 4037
Author(s):  
Su Yeon Seo ◽  
Se Kyun Bang ◽  
Suk Yun Kang ◽  
Seong Jin Cho ◽  
Kwang Ho Choi ◽  
...  
Keyword(s):  
Negative Emotions ◽  
Acupuncture Point ◽  
Repeated Administration ◽  
Ultrasonic Vocalizations ◽  
Corticotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Alcohol Administration ◽  
Heart Meridian ◽  
Mature Brain ◽  
Neurotropic Factor

The Shenmen point (acupuncture point heart 7: HT7), located in the heart meridian, is frequently used to treat mental disorders, including drug addiction, anxiety, and depression. This study aimed to determine how HT7 regulates anxiety and negative emotions caused by repeated alcohol administration, focusing on the amygdala and paraventricular nucleus (PVN). Repeated administration of alcohol (ETOH; 2 g/kg, i.p. injection, 16% v/v) for 14 days increased the corticosterone (CORT) levels, and HT7 stimulation reduced the plasma CORT levels. HT7 stimulation mitigated anxiety-like behaviors and reduced 22-kHz ultrasonic vocalizations in rats receiving repeated ETOH injections. HT7 stimulation increased the amygdala expression of mature brain-derived neurotropic factor (mBDNF) and phosphorylated tropomyosin receptor kinase B (pTrkB) and decreased the PVN corticotropin-releasing hormone (CRH) expression. Amygdala microinjections of the TrkB antagonist ANA-12 (0.1 pmol/1 μL) reversed the increase in PVN CRH levels. The reduced PVN CRH levels were regulated by CRH-expressing neurons in the amygdala, and the increased amygdala CRH levels were affected by the HT7-stimulation induced increases in mBDNF. HT7 stimulation alleviates increased stress hormone levels and mitigates anxiety and negative emotions caused by repeated ETOH administration. These results provide scientific support for the clinical use of acupuncture to treat various alcoholism-induced diseases.

THE EFFECT OF CHRONIC ALCOHOL ADMINISTRATION UPON CARDIAC NUCLEOTIDE CONCENTRATIONS AND HISTOMORPHOMETRY

1994 ◽  
Vol 22 (3) ◽  
pp. 352S-352S
Author(s):  
VINOOD B. PATEL ◽  
JONATHAN R. SALISBURY ◽  
LORETA M. RODRIGUES ◽  
JOHN R. GRIFFITHS ◽  
PETER J. RICHARDSON ◽  
...  
Keyword(s):  
Chronic Alcohol ◽  
Alcohol Administration ◽  
Chronic Alcohol Administration

scholarly journals Acute and chronic alcohol administration: Effects on performance of zebrafish in a latent learning task

2015 ◽  
Vol 282 ◽  
pp. 76-83 ◽  
Author(s):  
Ana C. Luchiari ◽  
Diana C. Salajan ◽  
Robert Gerlai
Keyword(s):  
Learning Task ◽  
Latent Learning ◽  
Chronic Alcohol ◽  
Alcohol Administration ◽  
Chronic Alcohol Administration

Naturalistic Follow-Up of Drinking Behavior Following Participation in an Alcohol Administration Study

1999 ◽  
Vol 17 (1-2) ◽  
pp. 159-162 ◽  
Author(s):  
Rajita Sinha ◽  
Suchitra Krishnan-Sarin ◽  
Conor Farren ◽  
Stephanie O'Malley
Keyword(s):  
Drinking Behavior ◽  
Alcohol Administration

Gelatin "Shots" as a New Method for Alcohol Administration in a Laboratory Setting

2006 ◽  
Vol 30 (3) ◽  
pp. 473-479 ◽  
Author(s):  
Elizabeth Ralevski ◽  
Ralitza Gueorguieva ◽  
Diana D. Limoncelli ◽  
Reema Husain ◽  
J. Serrita Jane ◽  
...  
Keyword(s):  
New Method ◽  
Laboratory Setting ◽  
Alcohol Administration

scholarly journals Self-amplified BDNF transcription is a regulatory system for synaptic maturation in cultured cortical neurons

2015 ◽  
Vol 91 ◽  
pp. 55-61 ◽  
Author(s):  
Shingo Nakajima ◽  
Tadahiro Numakawa ◽  
Naoki Adachi ◽  
Yoshiko Ooshima ◽  
Haruki Odaka ◽  
...  
Keyword(s):  
Cortical Neurons ◽  
Regulatory System ◽  
Cultured Cortical Neurons ◽  
Synaptic Maturation ◽  
Bdnf Transcription
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