RNA thiolation level (incorporation of methionine-S35) in peripheral lymphocytes of donors and patients with chronic lymphatic leukemia

1973 ◽  
Vol 76 (6) ◽  
pp. 1430-1431
Author(s):  
N. A. Fedorov ◽  
N. V. Biryukova ◽  
R. �. Kimeral
1973 ◽  
Vol 138 (4) ◽  
pp. 798-811 ◽  
Author(s):  
Gordon D. Ross ◽  
Margaret J. Polley ◽  
Enrique M. Rabellino ◽  
Howard M. Grey

In the present study it was shown that normal peripheral lymphocytes have two different complement receptors: one for C3b (the immune adherence receptor) and one for C3b subsequent to its cleavage by C3b inactivator. The two receptors are not cross-reactive and were shown by tests with various antisera to be antigenically distinct. Both the immune adherence receptor and the receptor for C3b inactivator-cleaved C3b were found on normal peripheral lymphocytes and on cultured lymphoblastoid cells. In 15 out of 18 chronic lymphatic leukemia patients, the immune adherence receptor was either partially or completely missing from the peripheral lymphocytes, while the lymphocyte receptor for C3b inactivator-cleaved C3b was retained. Normal erythrocytes, on the other hand, were found to have only the immune adherence receptor. Granulocytes from normal peripheral blood appeared to have only a receptor for C3b and did not have a receptor for C3b inactivator-cleaved C3b.


1975 ◽  
Vol 54 (5) ◽  
pp. 306-311 ◽  
Author(s):  
A. Klajman ◽  
A. Yaretzky ◽  
J. Manor ◽  
Z. Steiner

Leukemia ◽  
2000 ◽  
Vol 14 (4) ◽  
pp. 754-766 ◽  
Author(s):  
T Pfitzner ◽  
A Engert ◽  
H Wittor ◽  
T Schinköthe ◽  
F Oberhäuser ◽  
...  

1986 ◽  
Vol 67 (2) ◽  
pp. 99-101
Author(s):  
V. Ya. Shustov ◽  
N. A. Afanasyeva ◽  
P. P. Kuznetsov ◽  
A. K. Myshkina

Chronic lymphatic leukemia is second only to acute leukemia in the frequency of infectious complications. In most cases, severe infectious complications are the cause of death in these patients. Modern chemotherapy makes it possible to preserve the ability to work and the life expectancy of patients for a long time. However, the negative effect of cytostatic drugs on the already altered immune system leads to an even greater suppression of immunity and an increase in the number of infectious complications. The search for new ways to combat infections has shown the advisability of long-term outpatient treatment with antibacterial drugs.


1984 ◽  
Vol 8 (2) ◽  
pp. 223-237
Author(s):  
Jean-Pierre Bergerat ◽  
Jean-Marie Lang ◽  
Salomon Levy ◽  
Marie-Marthe Tongio ◽  
Francoise Uettwiller ◽  
...  

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