Sympathetic and parasympathetic regulation of the heart during transient coronary insufficiency

1990 ◽  
Vol 109 (1) ◽  
pp. 21-23
Author(s):  
P. F. Litvitskii
Keyword(s):  
Coronary Insufficiency ◽  
Transient Coronary Insufficiency ◽  
Parasympathetic Regulation ◽  
Sympathetic And Parasympathetic Regulation

Sympathetic and Parasympathetic Regulation of Rectal Motility in Rats

2009 ◽  
Vol 13 (11) ◽  
pp. 2027-2033 ◽  
Author(s):  
Timothy J. Ridolfi ◽  
Wei-Dong Tong ◽  
Toku Takahashi ◽  
Lauren Kosinski ◽  
Kirk A. Ludwig
Keyword(s):  
Rectal Motility ◽  
Parasympathetic Regulation ◽  
Sympathetic And Parasympathetic Regulation

Cardiac pacemakers in absence of the SA node: responses to exercise and autonomic blockade

1978 ◽  
Vol 234 (4) ◽  
pp. H465-H470 ◽  
Author(s):  
W. C. Randall ◽  
J. Talano ◽  
M. P. Kaye ◽  
D. Euler ◽  
S. Jones ◽  
...  
Keyword(s):  
Surgical Excision ◽  
P Wave ◽  
Cardiac Pacemakers ◽  
Complete Excision ◽  
Sinus Arrhythmia ◽  
Sa Node ◽  
Autonomic Blockade ◽  
Parasympathetic Regulation ◽  
Sympathetic And Parasympathetic Regulation ◽  
Atrial Rhythm

Surgical excision of the sinoatrial node, verified histologically, is followed by a supraventricular (atrial) rhythm in both resting and exercising dog whether anesthetized or conscious. The ECG is characterized by a definitive P wave and associated atrial electrograms. Waxing and waning in heart rate, generally referred to as sinus arrhythmia continues in the awake animal after complete excision of the SA node. This arrhythmia is responsive to both adrenergic and cholinergic interventions, thus indicating the presence of both sympathetic and parasympathetic regulation of subsidiary atrial pacemaking tissues.

scholarly journals Physiological cAMP-elevating secretagogues differentially regulate fluid and protein secretions in mouse submandibular and sublingual glands

2019 ◽  
Vol 316 (5) ◽  
pp. C690-C697 ◽  
Author(s):  
Yusuke Kondo ◽  
James E. Melvin ◽  
Marcelo A. Catalan
Keyword(s):  
Vasoactive Intestinal Peptide ◽  
Ex Vivo ◽  
Sympathetic Innervation ◽  
Fluid Secretion ◽  
Intracellular Camp ◽  
Functional Differences ◽  
Parasympathetic Regulation ◽  
G Protein Coupled ◽  
Dependent Pathway ◽  
Sympathetic And Parasympathetic Regulation

The mechanisms underlying the functional differences in sympathetic and parasympathetic regulation of the major salivary glands have received little attention. The acute effects of parasympathetic muscarinic (carbachol)-dependent and combined parasympathetic-dependent plus cAMP-dependent pathways on fluid secretion rates, ion composition, and protein content were assessed using a newly developed ex vivo preparation that allows the simultaneous perfusion of the mouse submandibular (SMGs) and sublingual glands (SLGs). Our results confirm that the muscarinic-dependent pathway accounts for the bulk of salivation in SMGs and SLGs, whereas costimulation with a cAMP-increasing agent (forskolin, isoproterenol, or vasoactive intestinal peptide) did not increase the flow rate. Costimulation with carbachol plus the β-adrenergic agonist isoproterenol decreased the concentration of NaCl and produced a substantial increase in the protein and Ca2+ content of SMG but not SLG saliva, consistent with a sparse sympathetic innervation of the SLGs. On the other hand, forskolin, which bypasses receptors to increase intracellular cAMP by directly activating the enzyme adenylate cyclase, enhanced the secretion of protein and Ca2+ by both the SMGs and SLGs. In contrast, isoproterenol and vasoactive intestinal peptide specifically stimulated protein secretion in SMG and SLG salivas, respectively. In summary, cAMP-dependent signaling does not play a major role in the stimulation of fluid secretion in SMGs and SLGs, whereas each cAMP-increasing agonist behaves differently in a gland-specific manner suggesting differential expression of G protein-coupled receptors in the epithelial cells of SMGs and SLGs.

Dynamics of some parameters of hemostasis in transient coronary insufficiency depending on the duration of myocardial ischemia

1983 ◽  
Vol 95 (1) ◽  
pp. 31-34 ◽  
Author(s):  
P. F. Litvitskii ◽  
G. A. Yakunin ◽  
L. A. Lavrova ◽  
A. V. Pleshanov ◽  
A. Ya. Smolyanitskii
Keyword(s):  
Myocardial Ischemia ◽  
Coronary Insufficiency ◽  
Transient Coronary Insufficiency
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