Hepatotoxicity from paraaminobenzoic acid

1991 ◽  
Vol 36 (12) ◽  
pp. 1793-1793 ◽  
Author(s):  
Marie Borum ◽  
Ephraim Nsien ◽  
Hyman Zimmerman

1944 ◽  
Vol 49 (2) ◽  
pp. 132 ◽  
Author(s):  
L. G. BEINHAUER


1944 ◽  
Vol 208 (3) ◽  
pp. 315-320 ◽  
Author(s):  
HAROLD BRANDALEONE ◽  
ELIZABETH MAIN ◽  
J. MURRAY STELLE


1953 ◽  
Vol 68 (6) ◽  
pp. 728 ◽  
Author(s):  
ALEXANDER A. FISHER


2020 ◽  
Vol 25 (4) ◽  
pp. 7-20
Author(s):  
Mercy Bamigboye ◽  
Ikechukwu P. Ejidike ◽  
Abdulbasit A. Aliyu

Four novel metal complexes of mixed amodiaquine and paraaminobenzoic acid have been synthesized using a standard method and confirmed by results of some physicochemical and spectroscopic techniques. Antimicrobial activities have been carried out on the complexes against some selected organisms: (antibacterial organisms: K. pneumonia, B. subtilis, E. coli, S. aureus, P. aeruginosa and S. faecalis) and (antifungal organisms: Candida albicans, Aspergillus niger and Penicillium chrysogenum) to determine their effectiveness. The complexes were evaluated for their toxicity level in wister rats. The Amodiaquine and Paraaminobenzoic acid produce complexes in ratio 1:1:1 in coordination with the metal ion. Octahedral geometry has been proposed for all the complexes. The complexes were found to be non-electrolytic in nature. The complexes were observed to be more active than their free ligands as determined by their zone of inhibition (nm). The complexes have been proved to be less toxic to the body.



1951 ◽  
Vol 63 (1) ◽  
pp. 115 ◽  
Author(s):  
CHRIS J. D. ZARAFONETIS


2010 ◽  
Vol 20 (2) ◽  
pp. 217-219 ◽  
Author(s):  
Johanna Stoevesandt ◽  
Natalie Kürzinger ◽  
Eva Bettina Bröcker ◽  
Axel Trautmann


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