Activation of adenosine A2 receptors enhances high K+-evoked taurine release from rat hippocampus: A microdialysis study

Amino Acids ◽  
1998 ◽  
Vol 15 (1-2) ◽  
pp. 43-52 ◽  
Author(s):  
Junichi Hada ◽  
T. Kaku ◽  
K. Morimoto ◽  
Y. Hayashi ◽  
K. Nagai
Keyword(s):  
Rat Hippocampus ◽  
Taurine Release ◽  
High K ◽  
Microdialysis Study ◽  
A2 Receptors

Adenosine transport inhibitors enhance high K+-evoked taurine release from rat hippocampus

1996 ◽  
Vol 305 (1-3) ◽  
pp. 101-107 ◽  
Author(s):  
Junichi Hada ◽  
Tomohiro Kaku ◽  
Kazuyoshi Morimoto ◽  
Yasumasa Hayashi ◽  
Kazuo Nagai
Keyword(s):  
Rat Hippocampus ◽  
Taurine Release ◽  
High K ◽  
Adenosine Transport ◽  
Transport Inhibitors

Weak organic acids induce taurine release through an osmotic-sensitive process in in vivo rat hippocampus

1990 ◽  
Vol 26 (2) ◽  
pp. 159-167 ◽  
Author(s):  
J. M. Solis ◽  
A. S. Herranz ◽  
O. Herreras ◽  
N. Menéndez ◽  
R. Martin del Rio
Keyword(s):  
Organic Acids ◽  
Rat Hippocampus ◽  
Taurine Release ◽  
Weak Organic Acids

Functional Roles of A1 and A2 Receptors in Rat Hippocampus and Striatum

1990 ◽  
pp. 194-199
Author(s):  
T. V. Dunwiddie ◽  
C. R. Lupica ◽  
W. A. Cass ◽  
N. R. Zahniser ◽  
M. Williams
Keyword(s):  
Rat Hippocampus ◽  
Functional Roles ◽  
A2 Receptors

High potassium induces taurine release by osmosensitive and osmoresistant mechanisms in the rat hippocampus in vivo

2009 ◽  
Vol 87 (1) ◽  
pp. 208-217 ◽  
Author(s):  
José A. Rodríguez-Navarro ◽  
Rafael Gonzalo-Gobernado ◽  
Antonio S. Herranz ◽  
José M. Gonźlez-Vigueras ◽  
José M. Solís
Keyword(s):  
Rat Hippocampus ◽  
Taurine Release ◽  
High Potassium

α-Sialylcholesterol enhances the depolarization-induced release of acetylcholine and glutamate in rat hippocampus: in vivo microdialysis study

2004 ◽  
Vol 357 (1) ◽  
pp. 9-12 ◽  
Author(s):  
Yasukazu Tanaka ◽  
Huiwan Han ◽  
Tairo Hagishita ◽  
Fumiko Fukui ◽  
Guoquan Liu ◽  
...  
Keyword(s):  
In Vivo Microdialysis ◽  
Rat Hippocampus ◽  
Release Of Acetylcholine ◽  
Microdialysis Study

Functional regulation by dopamine receptors of serotonin release from the rat hippocampus: in vivo microdialysis study

1996 ◽  
Vol 353 (6) ◽  
pp. 621-629 ◽  
Author(s):  
Machiko Matsumoto ◽  
Mitsuhiro Yoshioka ◽  
Hiroko Togashi ◽  
Toshiya Ikeda ◽  
Hideya Saito
Keyword(s):  
Dopamine Receptors ◽  
In Vivo Microdialysis ◽  
Serotonin Release ◽  
Rat Hippocampus ◽  
Functional Regulation ◽  
Microdialysis Study

Sodium nitroprusside-induced seizure and taurine release from rat hippocampus

Amino Acids ◽  
2000 ◽  
Vol 19 (3-4) ◽  
pp. 547-559 ◽  
Author(s):  
J. Hada ◽  
T. Kaku ◽  
M.-H. Jiang ◽  
K. Morimoto ◽  
Y. Hayashi ◽  
...  
Keyword(s):  
Sodium Nitroprusside ◽  
Rat Hippocampus ◽  
Taurine Release

Kainate seizures increase nociceptin/orphanin FQ release in the rat hippocampus and thalamus: a microdialysis study

2004 ◽  
Vol 91 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Liliana Carmona Aparicio ◽  
Sanzio Candeletti ◽  
Anna Binaschi ◽  
Manuela Mazzuferi ◽  
Simona Mantovani ◽  
...  
Keyword(s):  
Rat Hippocampus ◽  
Orphanin Fq ◽  
Microdialysis Study

scholarly journals Volume-dependent taurine release from cultured astrocytes requires permissive [Ca2+]iand calmodulin

1999 ◽  
Vol 277 (4) ◽  
pp. C823-C832 ◽  
Author(s):  
Alexander A. Mongin ◽  
Zhaohui Cai ◽  
Harold K. Kimelberg
Keyword(s):  
Cell Swelling ◽  
Transport Systems ◽  
Channel Blockers ◽  
Organic Osmolytes ◽  
Taurine Release ◽  
Cultured Astrocytes ◽  
High K ◽  
Intracellular Ca ◽  
Free Media ◽  
Taurine Efflux

Cell swelling results in regulatory activation of multiple conductive anion pathways permeable toward a broad spectrum of intracellular organic osmolytes. Here, we explore the involvement of extracellular and intracellular Ca2+ in volume-dependent [3H]taurine efflux from primary cultured astrocytes and compare the Ca2+ sensitivity of this efflux in slow (high K+ medium induced) and fast (hyposmotic medium induced) cell swelling. Neither Ca2+-free medium nor Ca2+-channel blockers prevented the volume-dependent [3H]taurine release. In contrast, loading cells with the membrane-permeable Ca2+ chelator 1,2-bis(2-aminophenoxy)ethane- N, N, N′, N′-tetraacetic acid (BAPTA)-AM suppressed [3H]taurine efflux by 65–70% and 25–30% under high-K+ and hyposmotic conditions, respectively. Fura 2 measurements confirmed that BAPTA-AM, but not Ca2+-free media, significantly reduced resting intracellular Ca2+concentration ([Ca2+]i). The calmodulin antagonists trifluoperazine and fluphenazine reversibly and irreversibly, respectively, inhibited the high-K+-induced [3H]taurine release, consistent with their known actions on calmodulin. In hyposmotic conditions, the effects were less pronounced. These data suggest that volume-dependent taurine release requires minimal basal [Ca2+]iand involves calmodulin-dependent step(s). Quantitative differences in Ca2+/calmodulin sensitivity of high-K+-induced and hyposmotic medium-induced taurine efflux are due to both the effects of the inhibitors on high-K+-induced cell swelling and their effects on transport systems and/or signaling mechanisms determining taurine efflux.

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