Ouabain-resistant mutants of Chinese hamster ovary cells are not directly affected in Na+, K+-ATPase

1986 ◽  
Vol 12 (4) ◽  
pp. 367-373 ◽  
Author(s):  
Arvind Chopra ◽  
Radhey S. Gupta
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells ◽  
Resistant Mutants

X-Ray Induction of 8-Azaguanine-Resistant Mutants in Synchronous Chinese Hamster Ovary Cells

1980 ◽  
Vol 83 (1) ◽  
pp. 146 ◽  
Author(s):  
R. F. Jostes ◽  
K. M. Bushnell ◽  
W. C. Dewey
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells ◽  
X Ray ◽  
Resistant Mutants

scholarly journals Identification and characterization of a third complementation group of emetine-resistant Chinese hamster cell mutants.

1981 ◽  
Vol 1 (1) ◽  
pp. 58-65 ◽  
Author(s):  
J J Wasmuth ◽  
J M Hill ◽  
L S Vock
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Chinese Hamster Cell ◽  
Resistant Cell ◽  
Complementation Group ◽  
Ovary Cells ◽  
Complementation Groups ◽  
Resistant Mutants ◽  
Biosynthetic Machinery

We have isolated emetine-resistant cell lines from Chinese hamster peritoneal fibroblasts and have shown that they represent a third distinct class or complementation group of emetine-resistant mutants, as determined by three different criteria. These mutants, like those belonging to the two other complementation groups we have previously defined, which were isolated from Chinese hamster lung and Chinese hamster ovary cells, have alterations that directly affect the protein biosynthetic machinery. So far, there is absolute cell line specificity with respect to the three complementation groups, in that all the emetine-resistant mutants we have isolated from Chinese hamster lung cells belong to one complementation group, all those we have isolated from Chinese hamster ovary cells belong to a second complementation group, and all those isolated from Chinese hamster peritoneal cells belong to a third complementation group. Thus, in cultured Chinese hamster cells, mutations in at least three different loci, designated emtA, emtB, and emtC, encoding for different components of the protein biosynthetic machinery, can give rise to the emetine-resistant phenotype.

Alanine-resistant mutants of Chinese hamster ovary cells, CHO-K1, producing increases in velocity of proline transport through the A, ASC, and P systems

1983 ◽  
Vol 9 (2) ◽  
pp. 189-213 ◽  
Author(s):  
John Moffett ◽  
Scott Curriden ◽  
Robert Ertsey ◽  
Elizabeth Mendiaz ◽  
Ellis Englesberg
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
P Systems ◽  
Ovary Cells ◽  
Proline Transport ◽  
Resistant Mutants
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