A combinatorial method for constructing libraries of long peptides displayed by filamentous phage

1995 ◽  
Vol 1 (1) ◽  
pp. 39-52 ◽  
Author(s):  
Tapio Haaparanta ◽  
William D. Huse
Keyword(s):  
Filamentous Phage ◽  
Combinatorial Method

scholarly journals NMR Protein Structure Calculation and Sphere Intersections

2020 ◽  
Vol 8 (1) ◽  
pp. 89-101
Author(s):  
Carlile Lavor ◽  
Rafael Alves ◽  
Michael Souza ◽  
Luis Aragón José
Keyword(s):  
Protein Structures ◽  
Structure Calculation ◽  
Bp Algorithm ◽  
Main Step ◽  
Combinatorial Method ◽  
Nmr Data ◽  
Sampling Process ◽  
Protein Molecules ◽  
Protein Structure Calculation ◽  
Branch And Prune

AbstractNuclear Magnetic Resonance (NMR) experiments can be used to calculate 3D protein structures and geometric properties of protein molecules allow us to solve the problem iteratively using a combinatorial method, called Branch-and-Prune (BP). The main step of BP algorithm is to intersect three spheres centered at the positions for atoms i − 3, i − 2, i − 1, with radii given by the atomic distances di−3,i, di−2,i, di−1,i, respectively, to obtain the position for atom i. Because of uncertainty in NMR data, some of the distances di−3,i should be represented as interval distances [{\underline{d}_{i - 3,i}},{\bar d_{i - 3,i}}], where {\underline{d}_{i - 3,i}} \le {d_{i - 3,i}} \le {\bar d_{i - 3,i}}. In the literature, an extension of the BP algorithm was proposed to deal with interval distances, where the idea is to sample values from [{\underline{d}_{i - 3,i}},{\bar d_{i - 3,i}}]. We present a new method, based on conformal geometric algebra, to reduce the size of [{\underline{d}_{i - 3,i}},{\bar d_{i - 3,i}}], before the sampling process. We also compare it with another approach proposed in the literature.

scholarly journals Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system.

1992 ◽  
Vol 267 (23) ◽  
pp. 16007-16010
Author(s):  
J.D. Marks ◽  
H.R. Hoogenboom ◽  
A.D. Griffiths ◽  
G Winter
Keyword(s):  
Immune System ◽  
Molecular Evolution ◽  
Filamentous Phage ◽  
Evolution Of Proteins

Biodistribution of filamentous phage-Fab in nude mice

1999 ◽  
Vol 225 (1-2) ◽  
pp. 171-178 ◽  
Author(s):  
Yum L Yip ◽  
Nicholas J Hawkins ◽  
Glenn Smith ◽  
Robyn L Ward
Keyword(s):  
Nude Mice ◽  
Filamentous Phage

scholarly journals Expanding the Versatility of Phage Display II: Improved Affinity Selection of Folded Domains on Protein VII and IX of the Filamentous Phage

PLoS ONE ◽  
2011 ◽  
Vol 6 (2) ◽  
pp. e17433 ◽  
Author(s):  
Geir Åge Løset ◽  
Norbert Roos ◽  
Bjarne Bogen ◽  
Inger Sandlie
Keyword(s):  
Phage Display ◽  
Filamentous Phage ◽  
Affinity Selection ◽  
Selection Of
Sign in / Sign up

Export Citation Format

Share Document