Comparison of hemodynamic data before and after corrective surgery for Down's syndrome and ventricular septal defect

1995 ◽  
Vol 10 (3) ◽  
pp. 154-157 ◽  
Author(s):  
Takahiro Kawai ◽  
Yukio Wada ◽  
Takeshi Enmoto ◽  
Katsuhiko Nishiyama ◽  
Kazuhiro Kitaura ◽  
...  
Keyword(s):  
Ventricular Septal Defect ◽  
Septal Defect ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Corrective Surgery ◽  
Before And After

Ventricular septal defect and Down's syndrome

The Lancet ◽  
1991 ◽  
Vol 337 (8735) ◽  
pp. 245-246 ◽  
Author(s):  
Bruno Marino ◽  
Antonio Corno ◽  
Paolo Guccione ◽  
Carlo Marcelletti
Keyword(s):  
Ventricular Septal Defect ◽  
Septal Defect ◽  
Down's Syndrome ◽  
Down’S Syndrome

Down's Syndrome and Heart Surgery

PEDIATRICS ◽  
1978 ◽  
Vol 61 (2) ◽  
pp. 331-331 ◽  
Author(s):  
Murray Feingold
Keyword(s):  
Congenital Heart Disease ◽  
Death Rate ◽  
Congenital Heart ◽  
Heart Surgery ◽  
Septal Defect ◽  
Ductus Arteriosus ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Corrective Surgery ◽  
Patent Ductus

The article by Greenwood and Nadas (Pediatrics 58:893, December 1976) may be misinterpreted. It states that the death rate in children with Down's syndrome and congenital heart disease is high. Although this is indeed true, the fact that the majority of these patients did not have corrective surgery must account for some of the high mortality. For example, of the ten patients with an isolated patent ductus arteriosus, six were not corrected. Also, 61 of the 66 patients with ventricular septal defect (VSD) did not have surgery.

Cleft of the mitral valve in patients with Down's syndrome

2002 ◽  
Vol 12 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Alain Fraisse ◽  
Tony Abdel Massih ◽  
Damien Bonnet ◽  
Daniel Sidi ◽  
Jean Kachaner
Keyword(s):  
Mitral Valve ◽  
Ventricular Septal Defect ◽  
Atrial Septal Defect ◽  
Septal Defect ◽  
Surgical Repair ◽  
Ductus Arteriosus ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Atrioventricular Septal Defect ◽  
Atrial Septal Defect Closure

Differentiation between a cleft of the mitral valve and the cleft of the left side of an atrioventricular septal defect – a lesion commonly found in patients with Down's syndrome – is surgically important since the distribution of the conduction tissue varies between the 2 lesions. We sought to determine if cleft of the mitral valve occurs also in patients with Down's syndrome. We studied 5 patients with Down's syndrome and cleft of the mitral valve followed in our institution. Echocardiography showed in all 5 patients a cleft dividing the anterior (aortic) leaflet of mitral valve with normal papillary muscle position, mural leaflet size, and ratio of the inlet/outlet dimension of the left ventricle. Associated cardiac lesions were present in all 5 patients: perimembranous ventricular septal defect in 3, ostium secundum atrial septal defect in 2 and patent ductus arteriosus in 2 patients. During the 5.6 years (0.2–11) of the follow-up period, surgical repair of the cleft was never indicated since the mitral regurgitation through the cleft remained mild or absent in all the patients. Two patients underwent closure of a ventricular septal defect, with atrial septal defect closure in one and ductal ligation in 2. One patient died suddenly at home, without evidence of a cardiac cause. In conclusion, a cleft of the mitral valve has important developmental and morphologic differences with atrioventricular septal defect and may occur in patients with Down's syndrome. If surgical repair of the cleft or of associated cardiac lesion is indicated, it is necessary to distinguish it from atrioventricular septal defect where the conduction axis is displaced posteriorly and may be exposed during surgery.

scholarly journals Aerococcus urinae causing Infective endocarditis in a patient with Down’s syndrome with ventricular septal defect

2021 ◽  
Author(s):  
Valentine LIETAERT ◽  
Georgeta CORNEA ◽  
Perrine KUCZERA-NAESSENS ◽  
Alexandre MONTMUREAU ◽  
Gisèle DEWULF ◽  
...  
Keyword(s):  
Risk Factors ◽  
Infective Endocarditis ◽  
Ventricular Septal Defect ◽  
Successful Treatment ◽  
Heart Surgery ◽  
Septal Defect ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Aerococcus Urinae

Aerococcus urinae is rare in infective endocarditis. The best known risk factors are urogenital comorbidities. We report the case of a 46-year-old male with Down’s syndrom with infective endocarditis. The patient underwent successful treatment with amoxicillin and heart surgery with valve replacement.He had an unknown ventricular septal defect

Comparison of Two Scales for Assessing Motor Development in Infants with down's Syndrome

1983 ◽  
Vol 3 (4) ◽  
pp. 213-221 ◽  
Author(s):  
Joan Snyder Lydic ◽  
Margaret A. Short ◽  
David L. Nelson
Keyword(s):  
Motor Development ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Motor Ability ◽  
Before And After ◽  
Partial Correlations ◽  
Depth Study ◽  
Movement Assessment ◽  
Stability Results

The Peabody Developmental Scales (PDS) and the Movement Assessment of Infants (MAI) were examined for their abilities to detect subtle changes in motor development of infants with Down's syndrome Both assessments were administered to 10 infants before and after a 6-week period A t-test suggested that the MAI was sensitive to developmental changes in the subjects tested from initial test to follow-up. Similar testing using the PDS did not reveal significant differences in the scores, suggesting that the MAI was the more sensitive of the two instruments. When partial correlations were calculated for possible artifactual effects due to age, the MAI still demonstrated greater stability. Results indicate that, for infants with Down's syndrome, the MAI may be preferable to the PDS for detecting changes in motor ability over short periods. However, these results should be considered tentative until a more in-depth study is conducted using a larger number of subjects from a variety of clinical populations.

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