Portal vein thrombosis in Crohn's disease

1991 ◽  
Vol 16 (1) ◽  
pp. 245-247 ◽  
Author(s):  
Don E. Brinberg ◽  
Thorarinn B. Stefansson ◽  
Francis A. Greicius ◽  
Sarwan S. Kahlam ◽  
Clifford Molin
2012 ◽  
Vol 16 (6) ◽  
pp. 1199-1203 ◽  
Author(s):  
Galen G. Leung ◽  
Muthu V. Sivasankaran ◽  
Jacqueline J. Choi ◽  
Celia M. Divino

1996 ◽  
Vol 10 (5) ◽  
pp. 297-300 ◽  
Author(s):  
Gad Friedman ◽  
Gary E Wild

Systemic amyloidosis and portal vein thrombosis are relatively rare complications of inflammatory bowel disease. The first case of a patient with Crohn’s disease presenting with both complications is presented. An acquired free protein S deficiency was disclosed in the patient, which may be responsible for the hypercoagulable state observed in Crohn’s disease and the nephrotic syndrome from amyloidosis.


2016 ◽  
Vol 10 (3) ◽  
pp. 589-595 ◽  
Author(s):  
Benjamin Heimgartner ◽  
Heather Dawson ◽  
Andrea De Gottardi ◽  
Reiner Wiest ◽  
Jan Hendrik Niess

Small intestinal bleeding in Crohn’s disease patients with noncirrhotic portal hypertension and partial portal and superior mesenteric vein thrombosis is a life-threatening event. Here, a case is reported in which treatment with azathioprine may have resulted in nodular regenerative hyperplasia, portal hypertension and portal vein thrombosis. The 56-year-old patient with Crohn’s disease developed nodular regenerative hyperplasia under treatment with azathioprine. He was admitted with severe bleeding. Gastroscopy showed small esophageal varices without bleeding stigmata. Blood was detected in the terminal ileum. CT scan revealed a partial portal vein thrombosis with extension to the superior mesenteric vein, thickening of the jejunal wall and splenomegaly. Because intestinal bleeding could not be controlled by conservative treatment, the thrombus was aspirated and a transjugular intrahepatic portosystemic shunt (TIPS) was placed. Switching the immunosuppressive medication to infliximab controlled Crohn’s disease activity. Bleeding was stopped, hemoglobin normalized, and thrombocytopenia and bowel movements improved. In summary, small intestinal bleeding in a Crohn’s patient with nodular regenerative hyperplasia, portal hypertension and portal vein thrombosis can be efficiently treated by TIPS. TIPS placement together with infliximab treatment led to the improvement of the blood panel and remission in this patient.


2019 ◽  
Vol 114 (1) ◽  
pp. S839-S840
Author(s):  
Minh Nguyen ◽  
Nicholas J. Helmstetter ◽  
Martin Sieloff ◽  
Tooba Tariq

1992 ◽  
Vol 68 (798) ◽  
pp. 291-293 ◽  
Author(s):  
A. Crowe ◽  
N. Taffinder ◽  
G. T. Layer ◽  
A. Irvine ◽  
R. J. Nicholls

Author(s):  
Minh Hoang Nam Nguyen ◽  
Eric Martin Sieloff ◽  
Tooba Tariq ◽  
Susan Faragher Bannon

2017 ◽  
Vol 55 (05) ◽  
pp. e28-e56
Author(s):  
B Scheiner ◽  
P Stammet ◽  
S Pokorny ◽  
T Bucsics ◽  
P Schwabl ◽  
...  

1985 ◽  
Vol 54 (03) ◽  
pp. 724-724 ◽  
Author(s):  
Géza Sas ◽  
György Blaskó ◽  
Iván Petrö ◽  
John H Griffin

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