scholarly journals Portal Vein Thrombosis and Systemic Amyloidosis in Crohn’s Disease: A Case Report and Review of the Literature

1996 ◽  
Vol 10 (5) ◽  
pp. 297-300 ◽  
Author(s):  
Gad Friedman ◽  
Gary E Wild
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Systemic Amyloidosis ◽  
Vein Thrombosis ◽  
First Case ◽  
S Deficiency ◽  
Inflammatory Bowel

Systemic amyloidosis and portal vein thrombosis are relatively rare complications of inflammatory bowel disease. The first case of a patient with Crohn’s disease presenting with both complications is presented. An acquired free protein S deficiency was disclosed in the patient, which may be responsible for the hypercoagulable state observed in Crohn’s disease and the nephrotic syndrome from amyloidosis.

Portal vein thrombosis in Crohn's disease

1991 ◽  
Vol 16 (1) ◽  
pp. 245-247 ◽  
Author(s):  
Don E. Brinberg ◽  
Thorarinn B. Stefansson ◽  
Francis A. Greicius ◽  
Sarwan S. Kahlam ◽  
Clifford Molin
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Vein Thrombosis

PROTEIN S DEFICIENCY WITH PORTAL VEIN THROMBOSIS : A CASE REPORT

2014 ◽  
Vol 1 (11) ◽  
pp. 1383-1386
Author(s):  
Kekathi Vidyasagar ◽  
Saifullah Quraishi S M ◽  
Ravi Theja ◽  
Chandrashekar S
Keyword(s):  
Case Report ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

Risk Factors of Portal Vein Thrombosis in Crohn’s Disease Patients

2012 ◽  
Vol 16 (6) ◽  
pp. 1199-1203 ◽  
Author(s):  
Galen G. Leung ◽  
Muthu V. Sivasankaran ◽  
Jacqueline J. Choi ◽  
Celia M. Divino
Keyword(s):  
Risk Factors ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Vein Thrombosis

scholarly journals A Rare Case of Portal Vein Thrombosis due to Protein S deficiency in a patient with Decompensated Cryptogenic CLD with Portal Hypertension, Completely Recanalized by Single Oral Anticoagulant-Rivaroxaban

2020 ◽  
pp. 29-37
Author(s):  
Richmond Ronald Gomes
Keyword(s):  
Portal Hypertension ◽  
Liver Disease ◽  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Oral Anticoagulant ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency ◽  
Hepatic Portal

Venous thromboembolic diseases are a group of heterogeneous diseases with different clinical forms and prognosis. Abdominal venous thrombosis may present either as Budd-Chiari syndrome (BCS) caused by hepatic vein or proximal inferior vena cava (IVC) obstruction or as an extra hepatic portal obstruction (EHPVO) caused by Portal vein thrombosis or mesenteric vein thrombosis. Portal vein thrombosis (PVT) is a rare form of venous thrombosis that affects the hepatic portal vein flow, which can lead to portal hypertension. Treatment of PVT includes anticoagulants, thrombolysis, and insertion of shunts, bypass surgery, and liver transplantation. Single anticoagulation therapy can be associated with a reduction in new thrombotic episodes. Here we experienced a 23 year old young lady with history of recent intrauterine death (IUD) diagnosed as PVT provoked by protein S deficiency with newly diagnosed decompensated cryptogenic chronic liver disease with portal hypertension. PVT was completely recanalized with single oral anticoagulant therapy rivaroxaban as initial low molecular weight heparin, enoxaparin administration caused reversible pancytopenia and there is a concern for bleeding and regular monitoring of INR with warfarin in this patient. Keywords: Portal vein thrombosis; Chronic liver disease; Protein S deficiency; Oral anticoagulant; Portal hypertension; Thrombolysis

A case of portal vein thrombosis associated with protein S deficiency

1993 ◽  
Vol 18 (2) ◽  
pp. 258 ◽  
Author(s):  
Bertrand Godeau ◽  
Catherine Leroy-Matheron ◽  
Michèle Gouault-Heilmann ◽  
Annette Schaeffer
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency

scholarly journals Recurrent esophagogastric variceal bleeding due to portal vein thrombosis caused by protein S deficiency

2018 ◽  
Vol 06 (11) ◽  
pp. E1283-E1288 ◽  
Author(s):  
Haoxiong Zhou ◽  
Jieying Xuan ◽  
Xianyi Lin ◽  
Yunwei Guo
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Variceal Bleeding ◽  
Endoscopic Therapy ◽  
Protein S ◽  
Protein S Deficiency ◽  
Esophageal Variceal ◽  
Vein Thrombosis ◽  
S Deficiency

Abstract Background and study aims Esophagogastric variceal bleeding (EGVB) is common in patients with portal vein thrombosis (PVT). Hereditary deficiencies in natural anticoagulant proteins, such as protein S, might contribute to PVT. However, recurrent EGVB caused by PVT in patients with protein S deficiency is seldom reported. Herein, we present the case of a 38-year-old man with protein S deficiency complicated with PVT. The patient suffered recurrent EGVB for 7 years. He underwent splenectomy plus pericardial revascularization and sequential endoscopic therapy, including one gastric variceal obturation (GVO) procedure and two esophageal variceal ligations (EVL) to eradicate the varices. Rivaroxaban was administrated to reduce risk of thrombotic events. The patient is currently well without rebleeding after 1 year of follow-up. To our knowledge there is no consensus on management of recurrent EGVB on the basis of thrombophilia complicated with PVT. According to our practice, sequential endoscopic therapy combined with anticoagulant appears to be effective and safe.

scholarly journals A Case of Protein S Deficiency Presented with Superior Mesenteric and Portal Vein Thrombosis

2002 ◽  
Vol 35 (2) ◽  
pp. 184-188 ◽  
Author(s):  
Yoshio Uemura ◽  
Kenji Kobayashi ◽  
Taichi Koyama ◽  
Naofumi Kagara ◽  
Yosuke Seki ◽  
...  
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Protein S ◽  
Protein S Deficiency ◽  
Vein Thrombosis ◽  
S Deficiency
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