Altered blood pressure response to propyldazine after repeated oral administration in conscious normotensive dogs: role of the renin-angiotensin system

1984 ◽  
Vol 79 (5) ◽  
pp. 588-597 ◽  
Author(s):  
S. Bacher ◽  
O. Kraupp ◽  
A. Beck ◽  
R. Seitelberger ◽  
G. Raberger
Keyword(s):  
Blood Pressure ◽  
Oral Administration ◽  
Blood Pressure Response ◽  
Renin Angiotensin System ◽  
Pressure Response ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Altered Blood

Relationship of blood pressure response and the renin-angiotensin system to first-dose prazosin

1985 ◽  
Vol 78 (2) ◽  
pp. 241-244 ◽  
Author(s):  
John P. Nicholson ◽  
Lawrence M. Resnick ◽  
Thomas G. Pickering ◽  
Rosemerie Marion ◽  
Patricia Sullivan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Response ◽  
Renin Angiotensin System ◽  
Pressure Response ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Relationship Of

Brain renin-angiotensin system modifies the blood pressure response to intracerebroventricular cadmium in rats

2010 ◽  
Vol 33 (3) ◽  
pp. 302-309 ◽  
Author(s):  
Maria V. Varoni ◽  
Domenico Palomba ◽  
Nicolò P. Macciotta ◽  
Elisabetta Antuofermo ◽  
Graziella Deiana ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Response ◽  
Renin Angiotensin System ◽  
Pressure Response ◽  
Angiotensin System ◽  
Renin Angiotensin

Role of renin-angiotensin system in glucocorticoid hypertension in rats

1982 ◽  
Vol 243 (1) ◽  
pp. E48-E51 ◽  
Author(s):  
H. Suzuki ◽  
M. Handa ◽  
K. Kondo ◽  
T. Saruta
Keyword(s):  
Blood Pressure ◽  
Intravenous Injection ◽  
Enzyme Inhibitor ◽  
Renin Angiotensin System ◽  
Plasma Renin ◽  
Dependent Manner ◽  
Concurrent Administration ◽  
Angiotensin System ◽  
Renin Angiotensin

The role of the renin-angiotensin system in the regulation of the blood pressure of dexamethasone-treated rats (Dex) was evaluated using saralasin, an angiotensin II antagonist, and SQ 14225 (SQ) (d-3-mercapto-2-methylpropranoyl-1-proline), an angiotensin-converting enzyme inhibitor. During a 7-day period blood pressure rose 65 +/- 10 mmHg (P less than 0.001) in Dex with no significant changes in plasma renin activity. Concurrent administration of dexamethasone and SQ attenuated the elevation of blood pressure (P less than 0.05). In the conscious, freely moving state, intravenous injection of SQ (10, 30, 100 micrograms/kg) reduced blood pressure of DEX in a dose-dependent manner (P less than 0.05). Also, intravenous injection of saralasin (10 micrograms.kg-1 . min-1) reduced blood pressure significantly (P less than 0.01). Bilateral nephrectomy abolished the effects of saralasin and SQ on blood pressure in Dex. These results indicate that the elevation of blood pressure in DEX depends partially on the renin-angiotensin system.

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