In vitro and in vivo uptake of nickel sulfides by rat lymphocytes

1991 ◽  
Vol 65 (4) ◽  
pp. 324-329 ◽  
Author(s):  
Hartmut F. Hildebrand ◽  
Anne-Marie Decaestecker ◽  
Fatima-Zohra Arrouijal ◽  
Robert Martinez
Keyword(s):  
Rat Lymphocytes ◽  
In Vivo Uptake

Study of Competitive Binding of Gallium and Iron by Tumor Cells

1984 ◽  
Vol 23 (06) ◽  
pp. 327-329
Author(s):  
M. C. Crone-Escanye ◽  
P. Thouvenot ◽  
J. Robert ◽  
L. J. Anghileri
Keyword(s):  
Tumor Cells ◽  
Competitive Binding ◽  
Tumor Uptake ◽  
Systemic Accumulation ◽  
In Vivo Uptake

SummaryThe influence of iron and gallium carriers on the in vitro and in vivo uptake of 67Ga and 59Fe by tumor cells has been studied. The results appear to indicate that ferritin might be involved in most of the systemic accumulation of 67Ga but that the mechanism of tumor uptake might be different.

Captopril (SQ 14,225): In vitro and in vivo influence on the proliferative response of rat lymphocytes

1982 ◽  
Vol 38 (3) ◽  
pp. 399-401 ◽  
Author(s):  
Lise Binderup ◽  
E. Bramm ◽  
E. Arrigoni-Martelli
Keyword(s):  
Proliferative Response ◽  
Rat Lymphocytes

scholarly journals Sulfate Uptake and Somatomedin Levels in the 'Little' (lit/lit) Mouse

1981 ◽  
Vol 34 (2) ◽  
pp. 221 ◽  
Author(s):  
NeiI M McKern ◽  
Donald B Cheek ◽  
WGordon Crewther
Keyword(s):  
Growth Hormone ◽  
Costal Cartilage ◽  
Fresh Medium ◽  
Bovine Growth Hormone ◽  
Consistent Difference ◽  
Sulfate Uptake ◽  
Low Levels ◽  
In Vivo Uptake

The mutant 'little' (lit/lit) mouse is deficient in growth hormone and has correspondingly low levels of serum somatomedin. Injection of these mice with human or bovine growth hormone significantly r(l.ises serum somatomedin levels within 6 h. In vivo uptake of radioactive sulfate by costal cartilage in lit/lit mice is similar to that of normal mice, which is unexpected in view of the low levels of circulating somatomedin. If costal cartilages from normal and lit/lit mice are preincubated in medium 199 in vitro before transfer to fresh medium containing radioactive sulfate and serum, there is no consistent difference in uptake of sulfate, demonstrating similar endogenous cartilage activity. In contrast, omission of the preincubation step reveals a lower uptake of sulfate in vitro by cartilage from lit/lit mice as compared with normal mice. Cartilage removed from lit/lit mice 24 h after injection with growth hormone, however, takes up greater amounts of sulfate than cartilage from untreated normal mice.

Further characterization of the antigen defined by the monoclonal antibody M27

1989 ◽  
Vol 94 (4) ◽  
pp. 725-731
Author(s):  
M.E. Bramwell ◽  
S.M. Humm
Keyword(s):  
Monoclonal Antibody ◽  
Culture Cells ◽  
Tissue Culture Cells ◽  
Reducing Conditions ◽  
Rat Lymphocytes ◽  
Foetal Liver ◽  
Cultivation In Vitro

Using immunoblotting techniques, the antigen that binds the monoclonal antibody M27 has been clearly defined in terms of apparent molecular mass and distribution. In reducing conditions it has an apparent mass of 178K (K = 10(3) Mr) and is present in the cytoplasm and membranes of all mammalian tissue culture cells so far examined. It is absent from lines derived from avian, piscine and amphibian sources. It is also absent from foetal liver of both rat and mouse, but subsequently appears after cultivation in vitro. Similarly, it can be detected on rat lymphocytes only after mitogenic stimulation. However, it is found on both hepatoma and lymphoma cells in vitro, and on in vivo tumours from murine sources. It thus appears to be associated with cell proliferation.

In vitro AND in vivo UPTAKE OF BENZOPORPHYRIN DERIVATIVE INTO HUMAN AND MINISWINE ATHEROSCLEROTIC PLAQUE

1993 ◽  
Vol 57 (4) ◽  
pp. 670-674 ◽  
Author(s):  
York N. Hsiang ◽  
M. Teresa Crespo ◽  
Anna M. Richter ◽  
Ashok K. Jain ◽  
Miguel Fragoso ◽  
...  
Keyword(s):  
Atherosclerotic Plaque ◽  
In Vivo Uptake
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