Angiotensin I converting enzyme inhibitors and the renal excretion of urate

1987 ◽  
Vol 1 (1) ◽  
pp. 29-38 ◽  
Author(s):  
William P. Leary ◽  
Ariel J. Reyes
Keyword(s):  
Renal Excretion ◽  
Enzyme Inhibitors ◽  
Converting Enzyme ◽  
Angiotensin I ◽  
Converting Enzyme Inhibitors ◽  
Angiotensin I Converting Enzyme

The Renal Antihypertensive Effect of Angiotensin I Converting Enzyme Inhibitors

1987 ◽  
Vol 5 (6) ◽  
pp. 705-710
Author(s):  
Shigeaki Matsukawa ◽  
Hiromichi Suzuki ◽  
Takao Saruta ◽  
Hiroo Kumagai
Keyword(s):  
Antihypertensive Effect ◽  
Enzyme Inhibitors ◽  
Converting Enzyme ◽  
Angiotensin I ◽  
Converting Enzyme Inhibitors ◽  
Angiotensin I Converting Enzyme

Thirst and brain angiotensin in cattle

1992 ◽  
Vol 262 (2) ◽  
pp. R204-R210
Author(s):  
J. R. Blair-West ◽  
D. A. Denton ◽  
M. J. McKinley ◽  
R. S. Weisinger
Keyword(s):  
Angiotensin Ii ◽  
Water Intake ◽  
Enzyme Inhibitors ◽  
Converting Enzyme ◽  
Preoptic Nucleus ◽  
Angiotensin I ◽  
Converting Enzyme Inhibitors ◽  
Median Preoptic Nucleus ◽  
Angiotensin I Converting Enzyme ◽  
Reduced Water

Cows that were normally hydrated or deprived of water were given intravenous or intracerebroventricular (icv) infusions of angiotensin I converting-enzyme inhibitors (CEI) or angiotensin II antagonists. Normally hydrated Na-deficient cows increased water intake in a dose-related manner in response to icv infusion of angiotensin I (n = 5). The response to 3 micrograms/h angiotensin I was abolished by concurrent icv infusion of the CEI captopril at 3 mg/h but not by intravenous infusion of captopril at 120 mg/h, which reduced Na appetite (n = 5). The icv infusion of captopril at 12 mg/h did not reduce the water intake of cows that were water restricted for 26.5 h (n = 4) or water restricted and Na deficient (n = 4). The icv infusion of the more lipophilic CEI ramipril at 3 mg/h (n = 7) did not reduce the water intake of normally hydrated or dehydrated cows but reduced the "need-free" intake of Na solution by dehydrated cows. The icv infusion of the nonpeptide antagonist Du Pont 753 at 3 mg/h (n = 7) reduced water intake in dehydrated cows. The results indicate that brain angiotensin may be involved in thirst in cattle. The data suggest that this brain angiotensin II may be formed by a pathway that does not include converting enzyme and that is sited inside the blood brain barrier, possibly in the median preoptic nucleus.

scholarly journals Angiotensin I-converting enzyme inhibitors derived from Ficus carica.

1989 ◽  
Vol 53 (10) ◽  
pp. 2763-2767 ◽  
Author(s):  
Susumu MARUYAMA ◽  
Shinsuke MIYOSHI ◽  
Hideoki TANAKA
Keyword(s):  
Enzyme Inhibitors ◽  
Ficus Carica ◽  
Converting Enzyme ◽  
Angiotensin I ◽  
Converting Enzyme Inhibitors ◽  
Angiotensin I Converting Enzyme
Sign in / Sign up

Export Citation Format

Share Document