Risk factors for rectal cancer morbidity and mortality in patients with familial adenomatous polyposis after colectomy and ileorectal anastomosis

2000 ◽  
Vol 43 (12) ◽  
pp. 1719-1725 ◽  
Author(s):  
Jan A. Björk ◽  
Helena I. Åkerbrant ◽  
Lennart E. Iselius ◽  
Rolf W. Hultcrantz
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Ileorectal Anastomosis ◽  
Morbidity And Mortality ◽  
Adenomatous Polyposis ◽  
Cancer Morbidity

Risk of Rectal Cancer in Patients After Colectomy and Ileorectal Anastomosis for Familial Adenomatous Polyposis

2003 ◽  
Vol 46 (9) ◽  
pp. 1175-1181 ◽  
Author(s):  
James Church ◽  
Carol Burke ◽  
Ellen McGannon ◽  
Olivia Pastean ◽  
Bryan Clark
Keyword(s):  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Ileorectal Anastomosis ◽  
Adenomatous Polyposis

scholarly journals Surgical treatment of familial adenomatous polyposis: ileoretal anastomosis or restorative proctolectomy?

2009 ◽  
Vol 46 (4) ◽  
pp. 294-299 ◽  
Author(s):  
Fábio Guilherme Campos ◽  
Rodrigo Oliva Perez ◽  
Antônio Rocco Imperiale ◽  
Víctor Edmond Seid ◽  
Sérgio Carlos Nahas ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Restorative Proctocolectomy ◽  
Ileorectal Anastomosis ◽  
Cumulative Risk ◽  
Oncological Outcome ◽  
Ileal Reservoir ◽  
Adenomatous Polyposis ◽  
Operative Complications

CONTEXT: Controversy regarding the best operative choice for familial adenomatous polyposis lays between the morbidity of restorative proctocolectomy and the supposed mortality due to rectal cancer after ileorectal anastomosis. OBJECTIVES: To evaluate operative complications and oncological outcome after ileorectal anastomosis and restorative proctocolectomy. METHODS: Charts from patients treated between 1977 and 2006 were retrospectively analyzed. Clinical and endoscopic data, results of treatment, pathological reports and information regarding early and late outcome were recorded. RESULTS: Eighty-eight patients - 41 men (46.6%) and 47 women (53.4%) - were assisted. At diagnosis, 53 patients (60.2%) already had associated colorectal cancer. Operative complications occurred in 25 patients (29.0 %), being 17 (19.7%) early and 8 (9.3%) late complications. There were more complications after restorative proctocolectomy (48.1%) compared to proctocolectomy with ileostomy (26.6%) and ileorectal anastomosis (19.0%) (P = 0,03). There was no operative mortality. During the follow-up of 36 ileorectal anastomosis, cancer developed in the rectal cuff in six patients (16,6%). Cumulative cancer risk after ileorectal anastomosis was 17.2% at 5 years, 24.1% at 10 years and 43.1% at 15 years of follow-up. Age-dependent cumulative risk started at 30 years (4.3%), went to 9.6% at 40 years, 20.9% at 40 years and 52% at 60 years. Among the 26 patients followed after restorative proctocolectomy, it was found cancer in the ileal pouch in 1 (3.8%). CONCLUSIONS: 1. Operative complications occurred in about one third of the patients, being more frequently after the confection of ileal reservoir; 2. greater age and previous colonic carcinoma were associated with the development of rectal cancer after ileorectal anastomosis; 3. patients treated by restorative proctocolectomy are not free from the risk of pouch degeneration; 4. the disease complexity and the various risk factors (clinical, endoscopic, genetic) indicate that the best choice for operative treatment should be based on individual features discussed by a specialist; 5. all patients require continuous and long-term surveillance during postoperative follow-up.

Long-Term Outcome of Metachronous Rectal Cancer Following Ileorectal Anastomosis for Familial Adenomatous Polyposis

2009 ◽  
Vol 14 (3) ◽  
pp. 500-505 ◽  
Author(s):  
Tomohiro Yamaguchi ◽  
Seiichiro Yamamoto ◽  
Shin Fujita ◽  
Takayuki Akasu ◽  
Yoshihiro Moriya
Keyword(s):  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Ileorectal Anastomosis ◽  
Adenomatous Polyposis ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Metachronous Rectal Cancer

Comparison of outcomes of ileal pouch-anal anastomosis for familial adenomatous polyposis with and without previous ileorectal anastomosis

2007 ◽  
Vol 95 (4) ◽  
pp. 494-498 ◽  
Author(s):  
A. C. von Roon ◽  
P. P. Tekkis ◽  
R. E. Lovegrove ◽  
K. F. Neale ◽  
R. K. S. Phillips ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Ileal Pouch ◽  
Ileorectal Anastomosis ◽  
Ileal Pouch Anal Anastomosis ◽  
Adenomatous Polyposis ◽  
Anal Anastomosis

Prevalence and risk factors for adenomas in the ileal pouch and the afferent loop after restorative proctocolectomy for patients with familial adenomatous polyposis

2013 ◽  
Vol 27 (10) ◽  
pp. 3816-3822 ◽  
Author(s):  
Elise Pommaret ◽  
Ariane Vienne ◽  
Jérémie H. Lefevre ◽  
Philippe Sogni ◽  
Christian Florent ◽  
...  
Keyword(s):  
Risk Factors ◽  
Familial Adenomatous Polyposis ◽  
Restorative Proctocolectomy ◽  
Ileal Pouch ◽  
Adenomatous Polyposis ◽  
Afferent Loop
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