Tumors of bone and soft tissue in ancient Egypt and Nubia: a synopsis of the detected cases

1986 ◽  
Vol 1 (3) ◽  
pp. 267-275 ◽  
Author(s):  
W. M. Pahl
Keyword(s):  
Soft Tissue ◽  
Ancient Egypt ◽  
Tumors Of Bone

Vascular tumors of bone and soft tissue

2013 ◽  
pp. 165-182
Author(s):  
Lester J. Layfield ◽  
Carlos W. Bedrossian ◽  
Julia R. Crim ◽  
Lucio Palombini
Keyword(s):  
Soft Tissue ◽  
Vascular Tumors ◽  
Tumors Of Bone

Spindle cell tumors of bone and soft tissue in infants and children

2013 ◽  
pp. 23-40
Author(s):  
Lester J. Layfield ◽  
Carlos W. Bedrossian ◽  
Julia R. Crim ◽  
Lucio Palombini
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Infants And Children ◽  
Tumors Of Bone ◽  
Spindle Cell Tumors ◽  
In Infants And Children

Osseous tumors of bone and soft tissue

2013 ◽  
pp. 198-219
Author(s):  
Lester J. Layfield ◽  
Carlos W. Bedrossian ◽  
Julia R. Crim ◽  
Lucio Palombini
Keyword(s):  
Soft Tissue ◽  
Tumors Of Bone

Phenotypic and molecular studies of giant-cell tumors of bone and soft tissue

2005 ◽  
Vol 36 (9) ◽  
pp. 945-954 ◽  
Author(s):  
Y LAU ◽  
A SABOKBAR ◽  
C GIBBONS ◽  
H GIELE ◽  
N ATHANASOU
Keyword(s):  
Soft Tissue ◽  
Giant Cell ◽  
Giant Cell Tumors ◽  
Molecular Studies ◽  
Tumors Of Bone

ONCOGENOUS RICKETS: POSSIBLE ELABORATION BY A TUMOR OF A HUMORAL SUBSTANCE INHIBITING TUBULAR REABSORPTION OF PHOSPHATE

PEDIATRICS ◽  
1973 ◽  
Vol 52 (3) ◽  
pp. 432-434
Author(s):  
Harold E. Harrison
Keyword(s):  
Vitamin D ◽  
Soft Tissue ◽  
Marked Reduction ◽  
Renal Tubule ◽  
Tubular Reabsorption ◽  
Hypophosphatemic Rickets ◽  
Tumor Excision ◽  
Vitamin D Resistant Rickets ◽  
Tumors Of Bone ◽  
Resistant Rickets

Pollack et al.1 have introduced the intriguing speculation that some rare tumors of mesenchymal origin release a humoral substance which inhibits tubular reabsorption of phosphate and through the resultant profound hypophosphatemia causes vitamin D unresponsive rickets and osteomalacia. There have been sufficient reports of hypophosphatemic vitamin D-resistant rickets and osteomalacia cured by removal of tumors of bone or soft tissue to support the inference that there is a causal relationship between such tumors and the hypophosphatemic rickets. The demonstration of marked reduction of tubular reabsorption of phosphate in such a patient and the dramatic rapid return of tubular reabsorption of phosphate to normal following tumor excision is certainly circumstantial evidence of the secretion by the tumor of an inhibitor of phosphate retrieval by the renal tubule.

Epithelioid and polygonal cell tumors of bone and soft tissue

2013 ◽  
pp. 275-302
Author(s):  
Lester J. Layfield ◽  
Carlos W. Bedrossian ◽  
Julia R. Crim ◽  
Lucio Palombini
Keyword(s):  
Soft Tissue ◽  
Polygonal Cell ◽  
Tumors Of Bone

Intramedullary chondroid tumors of bone: correlation of abnormal peritumoral marrow and soft-tissue MRI signal with tumor type

1997 ◽  
Vol 26 (2) ◽  
pp. 100-106 ◽  
Author(s):  
L. Janzen ◽  
P. M. Logan ◽  
J. X. O'Connell ◽  
D. G. Connell ◽  
P. L. Munk
Keyword(s):  
Soft Tissue ◽  
Tumor Type ◽  
Tumors Of Bone

p63 Expression in Giant Cell–Containing Lesions of Bone and Soft Tissue

2011 ◽  
Vol 135 (6) ◽  
pp. 776-779 ◽  
Author(s):  
Gustavo de la Roza
Keyword(s):  
Soft Tissue ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Predictive Value ◽  
Cell Tumor ◽  
Bone Cysts ◽  
Giant Cell Tumors ◽  
Aneurysmal Bone Cysts ◽  
Tumors Of Bone ◽  
Pigmented Villonodular

Abstract Context.—Previous studies have demonstrated p63 overexpression in giant cell tumors of bone and advocate its use as a potential diagnostic marker. Although routine histology is often all that is required to diagnose giant cell tumor of bone, immunohistochemistry could prove useful to distinguish it from other benign and malignant giant cell–containing lesions of bone and soft tissue on needle biopsies and unusual clinical settings. Objective.—To assess p63 expression in giant cell–containing lesions of bone and soft tissue. Design.—p63 immunohistochemistry was performed in 23 giant cell tumors of bone, 8 primary aneurysmal bone cysts, 12 chondroblastomas, 4 giant cell reparative granulomas, 4 osteosarcomas, 15 tenosynovial giant cell tumors, 6 nonossifying fibromas, and 4 pigmented villonodular synovitides. Results.—p63 overexpression was identified in 20 of 23 giant cell tumors of bone (86.9%), 5 of 8 primary aneurysmal bone cysts (62.5%), 10 of 12 chondroblastomas (83.3%), 4 of 4 giant cell reparative granulomas (100%), 2 of 4 osteosarcomas (50%), 1 of 15 tenosynovial giant cell tumors (6.6%), 1 of 6 nonossifying fibromas (16.6%), and 1 of 4 pigmented villonodular synovitides (25%). The sensitivity, specificity, positive predictive value, and negative predictive value of p63 immunohistochemistry for the diagnosis of giant cell tumor of bone were 86.95%, 53.36%, 45.45%, and 91.17%, respectively. Conclusions.—This study shows that although p63 is expressed by most giant cell tumors of bone, its lack of specificity limits its use as an immunohistochemical marker in the differential diagnosis of giant cell–containing lesions of bone and soft tissue.

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