Levels of the thymic factor thymalin in human and murine skin epithelia during ontogeny

1996 ◽  
Vol 122 (5) ◽  
pp. 1147-1149
Author(s):  
I. I. Kalinina ◽  
Z. S. Khlystova ◽  
V. Kh. Khavinson ◽  
V. Yu. Arshinov ◽  
G. T. Sukhikh
Keyword(s):  
Author(s):  
H. Alasam

The possibility that intrathymic T-cell differentiation involves stem cell-lymphoid interactions in embryos led us to study the ultrastructure of epithelial cell in normal embryonic thymus. Studies in adult thymus showed that it produces several peptides that induce T-cell differentiation. Several of them have been chemically characterized, such as thymosin α 1, thymopoietin, thymic humoral factor or the serum thymic factor. It was suggested that most of these factors are secreted by populations of A and B-epithelial cells.Embryonic materials were obtained from inbred matings of Swiss Albino mice. Thymuses were disected from embryos 17 days old and prepared for transmission electron microscopy. Our studies showed that embryonic thymus at this stage contains undifferentiated and differentiated epithelial cells, large lymphoblasts, medium and few small lymphocytes (Fig. 5). No differences were found between cortical and medullary epithelial cells, in contrast to the findings of Van Vliet et al,. Epithelial cells were mostly of the A-type with low electron density in both cytoplasm and nucleus. However few B-type with high electron density were also found (Fig. 7).


1975 ◽  
Vol 249 (1 Thymus Factor) ◽  
pp. 316-327 ◽  
Author(s):  
Marie-Anne Bach ◽  
Catherine Fournier ◽  
Jean-François Bach

Author(s):  
L.N. GASTINEL ◽  
M. DARDENNE ◽  
J.M. PLEAU ◽  
J.F. BACH

1988 ◽  
Vol 6 (1) ◽  
pp. 17-25 ◽  
Author(s):  
V. J. Tomazic ◽  
C. R. Sacasa ◽  
A. Loftus ◽  
C. S. Suter ◽  
G. E. Elias

Cell ◽  
1981 ◽  
Vol 24 (3) ◽  
pp. 885-895 ◽  
Author(s):  
Koichi Kato ◽  
Shuichi Ikeyama ◽  
Muneo Takaoki ◽  
Akio Shino ◽  
Masao Takeuchi ◽  
...  

1977 ◽  
Vol 7 (12) ◽  
pp. 836-840 ◽  
Author(s):  
Giulia C.B. Astaldi ◽  
A. Astaldi ◽  
Marjorie Groenewoud ◽  
P. Wijermans ◽  
P.Th.A. Schellekens ◽  
...  

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