Chiral separation of tryptophan enantiomers by liquid chromatography with BSA-silica stationary phase

2000 ◽  
Vol 5 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Kwonil Kim ◽  
Kisay Lee
Keyword(s):  
Liquid Chromatography ◽  
Stationary Phase ◽  
Chiral Separation ◽  
Tryptophan Enantiomers

Chiral separation of three agrochemical toxins enantiomers by high-performance liquid chromatography on a vancomycin crystalline degradation products-chiral stationary phase

2007 ◽  
Vol 21 (3) ◽  
pp. 234-240 ◽  
Author(s):  
Mohammad Majid Mojtahedi ◽  
Sohila Chalavi ◽  
Alireza Ghassempour ◽  
Kourosh Tabar-Heydar ◽  
Seyed Javad Ghotb Sharif ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Stationary Phase ◽  
Chiral Separation ◽  
High Performance ◽  
Chiral Stationary Phase ◽  
Degradation Products

Chiral Separation of 3,4-dihydropyrimidin-2(1H)-ones and 3,4-di -hydropyrimidin- 2(1H)-thiones Enantiomers by HPLC on Chiralcel®OD-H

2020 ◽  
Vol 16 (3) ◽  
pp. 250-255
Author(s):  
Noura Kichou ◽  
Ismahan Rahou ◽  
Zaid M. Elamin ◽  
Khaled Sekkoum ◽  
Nasser Belboukhari ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Stationary Phase ◽  
Chiral Separation ◽  
Chiral Stationary Phase ◽  
Normal Phase ◽  
Good Resolution ◽  
Mode Structure ◽  
Structure Retention ◽  
Short Time

Objective: Ten racemic 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin- 2(1H)-thiones were separated by liquid chromatography on Chiralcel®OD-H column containing cellulose tris(3, 5-dimethylphenylcarbamate). Methods: The enantioseparation was carried out using Chiralcel®OD-H polysaccharide-type chiral stationary phase to resolve such enantiomers under normal-phase mode. Results: Complete separations of the 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin- 2(1H)-thiones derivatives with good resolution (RS= 1.04-2.80) were achieved within a short time (10-15 min). Conclusion: An optimal baseline separation (Rs> 1.5) was achieved using Chiralcel®OD-H under normal-phase mode. Structure-retention relationships have also been discussed.

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