The history of the cellular slime moulds as a “model system≓ for developmental biology

1999 ◽  
Vol 24 (1) ◽  
pp. 7-12 ◽  
Author(s):  
J. T. Bonner
Keyword(s):  
Developmental Biology ◽  
Model System ◽  
Slime Moulds ◽  
History Of ◽  
Cellular Slime ◽  
Cellular Slime Moulds

Acrasin, the Chemotactic Agent in Cellular Slime Moulds

1956 ◽  
Vol 33 (4) ◽  
pp. 645-657
Author(s):  
B. M. SHAFFER
Keyword(s):  
Room Temperature ◽  
Dialysis Membrane ◽  
Relay System ◽  
Highly Active ◽  
Slime Moulds ◽  
Cellular Slime ◽  
Set Up ◽  
Cellular Slime Moulds ◽  
Extracellular Slime ◽  
Do So

1. A study has been made of acrasin, the agent inducing chemotaxis in the amoebae of cellular slime moulds. 2. A method has been developed for subjecting sensitive amoebae to a fluctuating gradient set up by an artificial source that can be renewed at intervals of as little as a few seconds with fresh test solution. 3. Amoebae orient to a gradient maintained with the cell-free liquid freshly obtained from the immediate surroundings of a natural source. 4. Acrasin solution as secreted loses its activity very rapidly at room temperature. 5. A highly active stable solid is obtained by drying methanolic culture extracts; it resists boiling and exposure to acids and alkalis. Its solubility decreases rapidly in passing up the alcohol series. 6. The original instability has been shown to be due to the presence of another extracellular slime-mould product, possibly an enzyme; it, unlike acrasin, cannot pass rapidly across a dialysis membrane, is heat labile, and can be precipitated by ammonium sulphate. 7. The advantages of the organism's itself inactivating acrasin are considered. 8. Some of the advantages of a source's releasing acrasin in pulses are discussed; but it is not essential for orientation for it to do so. 9. Sensitive amoebae not only are oriented by an acrasin solution but are caused to secrete acrasin: this is the basis of a chemotactic relay system.

Vertebrates as vectors of cellular slime moulds in temperate forests

1992 ◽  
Vol 96 (8) ◽  
pp. 670-672 ◽  
Author(s):  
Steven L. Stephenson ◽  
John C. Landolt
Keyword(s):  
Temperate Forests ◽  
Slime Moulds ◽  
Cellular Slime ◽  
Cellular Slime Moulds

Implications of enzyme kinetics

2003 ◽  
Vol 31 (3) ◽  
pp. 719-722 ◽  
Author(s):  
A.G. McDonald
Keyword(s):  
Calcium Concentration ◽  
Calcium Oscillations ◽  
Rate Laws ◽  
Sustained Oscillations ◽  
Slime Moulds ◽  
Cellular Slime ◽  
The Many ◽  
Oxidase Reaction ◽  
Signalling Systems ◽  
Cellular Slime Moulds

Of the many examples of oscillatory kinetic behaviour known, several are briefly reviewed, including those of glycolysis, the peroxidase–oxidase reaction and oscillations in cellular calcium concentration. It is shown that simple mathematical models employing allosteric rate laws are sufficient to explain the instability of the steady state and the appearance of sustained oscillations. The cAMP-signalling systems of cellular slime moulds and the dynamics of intracellular calcium oscillations illustrate the importance of such oscillophores to inter- and intra-cellular communication and differentiation.

Development and Differentiation in the Cellular Slime Moulds

1978 ◽  
Vol 6 (5) ◽  
pp. 1098-1099
Author(s):  
JENNIFER DEE
Keyword(s):  
Slime Moulds ◽  
Development And Differentiation ◽  
Cellular Slime ◽  
Cellular Slime Moulds

Interspecific Spore Inhibition in the Cellular Slime Moulds

Nature ◽  
1966 ◽  
Vol 209 (5028) ◽  
pp. 1152-1152 ◽  
Author(s):  
HOWARD M. SNYDER ◽  
COSTANTSE CECCARINI
Keyword(s):  
Slime Moulds ◽  
Cellular Slime ◽  
Cellular Slime Moulds
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