Chemistry and biology of ras farnesyltransferase

Archives of Pharmacal Research ◽

10.1007/bf02976989 ◽

2002 ◽

Vol 25 (6) ◽

pp. 759-769 ◽

Author(s):

Kwang -Nym Cho ◽

Kee -In Lee

Keyword(s):

Ras Farnesyltransferase

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Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.8.3333 ◽

1995 ◽

Vol 92 (8) ◽

pp. 3333-3337 ◽

Author(s):

M. Hara ◽

M. Han

Keyword(s):

Caenorhabditis Elegans ◽

Farnesyltransferase Inhibitors ◽

Ras Mutation ◽

Ras Farnesyltransferase

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ChemInform Abstract: TAN-1813, a Novel Ras-Farnesyltransferase Inhibitor Produced by Phoma sp. Taxonomy, Fermentation, Isolation and Biological Activities in vitro and in vivo.

10.1002/chin.200103218 ◽

2001 ◽

Vol 32 (3) ◽

pp. no-no

Author(s):

Takafumi Ishii ◽

Kozo Hayashi ◽

Tsuneaki Hida ◽

Yasuharu Yamamoto ◽

Yukimasa Nozaki

Keyword(s):

Biological Activities ◽

Farnesyltransferase Inhibitor ◽

Ras Farnesyltransferase

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ChemInform Abstract: Synthesis and in vitro Evaluation of the Ras Farnesyltransferase Inhibitor Pepticinnamin E.

10.1002/chin.199831212 ◽

2010 ◽

Vol 29 (31) ◽

pp. no-no

Author(s):

K. HINTERDING ◽

P. HAGENBUCH ◽

J. RETEY ◽

H. WALDMANN

Keyword(s):

Farnesyltransferase Inhibitor ◽

In Vitro Evaluation ◽

Ras Farnesyltransferase

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Synthese und In-vitro-Evaluierung des Ras-Farnesyltransferase-Inhibitors Pepticinnamin E

Angewandte Chemie ◽

10.1002/(sici)1521-3757(19980504)110:9<1298::aid-ange1298>3.0.co;2-b ◽

1998 ◽

Vol 110 (9) ◽

pp. 1298-1301 ◽

Author(s):

Klaus Hinterding ◽

Patrizia Hagenbuch ◽

Janos Rétey ◽

Herbert Waldmann

Keyword(s):

Farnesyltransferase Inhibitors ◽

Ras Farnesyltransferase

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Ras farnesyltransferase inhibitors

Drugs of the Future ◽

10.1358/dof.1999.024.10.858630 ◽

1999 ◽

Vol 24 (10) ◽

pp. 1099 ◽

Author(s):

D.M. Leonard ◽

J.S. Sebolt-Leopold

Keyword(s):

Farnesyltransferase Inhibitors ◽

Ras Farnesyltransferase

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Manumycin A, Inhibitor of ras Farnesyltransferase, Inhibits Proliferation and Migration of Rat Vascular Smooth Muscle Cells

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1999.1546 ◽

1999 ◽

Vol 264 (3) ◽

pp. 915-920 ◽

Author(s):

Hirosuke Kouchi ◽

Kazufumi Nakamura ◽

Kazuo Fushimi ◽

Masakiyo Sakaguchi ◽

Masahiro Miyazaki ◽

...

Keyword(s):

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Muscle Cells ◽

Ras Farnesyltransferase ◽

And Migration ◽

Proliferation And Migration

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An Assessment of Bio-active Conformation of CAAX-based Tetrapeptide in Ras Farnesyltransferase Inhibition

Bulletin of the Korean Chemical Society ◽

10.5012/bkcs.2005.26.2.327 ◽

2005 ◽

Vol 26 (2) ◽

pp. 327-330

Keyword(s):

Active Conformation ◽

Ras Farnesyltransferase

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Balancing the Production of Two Recombinant Proteins inEscherichia coliby Manipulating Plasmid Copy Number: High-Level Expression of Heterodimeric Ras Farnesyltransferase

Protein Expression and Purification ◽

10.1006/prep.1997.0794 ◽

1997 ◽

Vol 11 (3) ◽

pp. 233-240 ◽

Author(s):

Kwei-Lan Tsao ◽

David S Waugh

Keyword(s):

Recombinant Proteins ◽

Copy Number ◽

Plasmid Copy Number ◽

High Level Expression ◽

Plasmid Copy ◽

Ras Farnesyltransferase ◽

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Ras-Farnesyltransferase-Inhibitors as Promising Anti-Tumor Drugs

Topics in Current Chemistry - Bioorganic Chemistry of Biological Signal Transduction ◽

10.1007/3-540-45035-1_4 ◽

2000 ◽

pp. 117-130 ◽

Author(s):

Herbert Waldmann ◽

Michael Thutewohl

Keyword(s):

Farnesyltransferase Inhibitors ◽

Ras Farnesyltransferase ◽

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Chapter 18. Ras Farnesyltransferase Inhibitors

Annual Reports in Medicinal Chemistry ◽

10.1016/s0065-7743(08)60457-1 ◽

1996 ◽

pp. 171-180 ◽

Author(s):

Semiramis Ayral-Kaloustian ◽

Jerauld S. Skotnicki

Keyword(s):

Farnesyltransferase Inhibitors ◽

Ras Farnesyltransferase

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