5-[123I]Iodo-A-85380: assessment of pharmacological safety, radiation dosimetry and SPECT imaging of brain nicotinic receptors in healthy human subjects

2004 ◽  
Vol 18 (4) ◽  
pp. 337-344 ◽  
Author(s):  
Masashi Ueda ◽  
Yasuhiko Iida ◽  
Takahiro Mukai ◽  
Marcelo Mamede ◽  
Koichi Ishizu ◽  
...  
Keyword(s):  
Nicotinic Receptors ◽  
Radiation Dosimetry ◽  
Human Subjects ◽  
Spect Imaging ◽  
Healthy Human ◽  
Healthy Human Subjects ◽  
Brain Nicotinic Receptors

scholarly journals Biodistribution and Radiation Dosimetry for the Tau Tracer 18 F-THK-5351 in Healthy Human Subjects

2017 ◽  
Vol 58 (9) ◽  
pp. 1498-1503 ◽  
Author(s):  
Ing-Tsung Hsiao ◽  
Kun-Ju Lin ◽  
Kuo-Lun Huang ◽  
Chin-Chang Huang ◽  
Han-Shiuan Chen ◽  
...  
Keyword(s):  
Radiation Dosimetry ◽  
Human Subjects ◽  
Healthy Human ◽  
Healthy Human Subjects

Biodistribution and radiation dosimetry of [ 123 I]ADAM in healthy human subjects: preliminary results

2003 ◽  
Vol 30 (1) ◽  
pp. 132-136 ◽  
Author(s):  
Tomi Kauppinen ◽  
Kim Bergström ◽  
Pertti Heikman ◽  
Jukka Hiltunen ◽  
Aapo Ahonen
Keyword(s):  
Radiation Dosimetry ◽  
Human Subjects ◽  
Healthy Human ◽  
Preliminary Results ◽  
Healthy Human Subjects

scholarly journals Safety, pharmacokinetics, metabolism and radiation dosimetry of 18F-tetrafluoroborate (18F-TFB) in healthy human subjects

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Huailei Jiang ◽  
Nicholas R. Schmit ◽  
Alex R. Koenen ◽  
Aditya Bansal ◽  
Mukesh K. Pandey ◽  
...  
Keyword(s):  
Radiation Dosimetry ◽  
Human Subjects ◽  
Healthy Human ◽  
Healthy Human Subjects

Brain SPECT imaging and whole-body biodistribution with [123I]ADAM — a serotonin transporter radiotracer in healthy human subjects

2006 ◽  
Vol 33 (2) ◽  
pp. 193-202 ◽  
Author(s):  
Kun-Ju Lin ◽  
Chia-Yih Liu ◽  
Shiaw-Pyng Wey ◽  
Ing-Tsung Hsiao ◽  
Jay Wu ◽  
...  
Keyword(s):  
Serotonin Transporter ◽  
Human Subjects ◽  
Brain Spect ◽  
Spect Imaging ◽  
Whole Body ◽  
Healthy Human ◽  
Healthy Human Subjects

Dynamic SPECT imaging after injection of the benzodiazepine receptor ligand [123I]iomazenil in healthy human subjects

1992 ◽  
Vol 45 (2) ◽  
pp. 67-77 ◽  
Author(s):  
Scott W. Woods ◽  
John P. Seibyl ◽  
Andrew W. Goddard ◽  
Holley M. Dey ◽  
Sami S. Zoghbi ◽  
...  
Keyword(s):  
Human Subjects ◽  
Benzodiazepine Receptor ◽  
Spect Imaging ◽  
Dynamic Spect ◽  
Healthy Human ◽  
Receptor Ligand ◽  
Healthy Human Subjects

Chronic stress decreases circulating endocannabinoid 2-arachidonoylglycerol in healthy human subjects

2015 ◽  
Author(s):  
Buqing Yi ◽  
Igor Nichiporuk ◽  
Matthias Feuerecker ◽  
Gustav Schelling ◽  
Alexander Chouker
Keyword(s):  
Chronic Stress ◽  
Human Subjects ◽  
Healthy Human ◽  
Healthy Human Subjects

scholarly journals Acacia Gum Is Well Tolerated While Increasing Satiety and Lowering Peak Blood Glucose Response in Healthy Human Subjects

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 618
Author(s):  
Riley Larson ◽  
Courtney Nelson ◽  
Renee Korczak ◽  
Holly Willis ◽  
Jennifer Erickson ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Human Subjects ◽  
Area Under The Curve ◽  
Soluble Fiber ◽  
Healthy Human ◽  
Glucose Response ◽  
Blood Glucose Response ◽  
Acacia Gum ◽  
Fiber Treatment ◽  
Healthy Human Subjects

Acacia gum (AG) is a non-viscous soluble fiber that is easily incorporated into beverages and foods. To determine its physiological effects in healthy human subjects, we fed 0, 20, and 40 g of acacia gum in orange juice along with a bagel and cream cheese after a 12 h fast and compared satiety, glycemic response, gastrointestinal tolerance, and food intake among treatments. Subjects (n = 48) reported less hunger and greater fullness at 15 min (p = 0.019 and 0.003, respectively) and 240 min (p = 0.036 and 0.05, respectively) after breakfast with the 40 g fiber treatment. They also reported being more satisfied at 15 min (p = 0.011) and less hungry with the 40 g fiber treatment at 30 min (p = 0.012). Subjects reported more bloating, flatulence, and GI rumbling on the 40 g fiber treatment compared to control, although values for GI tolerance were all low with AG treatment. No significant differences were found in area under the curve (AUC) or change from baseline for blood glucose response, although actual blood glucose with 20 g fiber at 30 min was significantly less than control. Individuals varied greatly in their postprandial glucose response to all treatments. AG improves satiety response and may lower peak glucose response at certain timepoints, and it is well tolerated in healthy human subjects. AG can be added to beverages and foods in doses that can help meet fiber recommendations.

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