Corticotropin-releasing hormone production by a small cell carcinoma in a patient with ACTH-dependent Cushing’s syndrome

1994 ◽  
Vol 17 (6) ◽  
pp. 447-452 ◽  
Author(s):  
Richard J. Auchus ◽  
G. Mastorakos ◽  
T. C. Friedman ◽  
G. P. Chrousos
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Cushing’S Syndrome ◽  
Cushing's Syndrome ◽  
Small Cell ◽  
Corticotropin Releasing Hormone ◽  
Hormone Production ◽  
Releasing Hormone

A Case of Small Cell Carcinoma of the Uterine Cervix Presenting Cushing's Syndrome

1996 ◽  
Vol 61 (3) ◽  
pp. 427-431 ◽  
Author(s):  
Akihiko Hashi ◽  
Takehiko Yasumizu ◽  
Ituo Yoda ◽  
Tomoko Kou ◽  
Kaoruko Mizuno ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Cushing’S Syndrome ◽  
Uterine Cervix ◽  
Cushing's Syndrome ◽  
Small Cell

scholarly journals Unusual Cushing’s Syndrome and Hypercalcitoninaemia due to a Small Cell Prostate Carcinoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Antonio Balestrieri ◽  
Elena Magnani ◽  
Fiorella Nuzzo
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Cushing’S Syndrome ◽  
Specific Antigen ◽  
Cushing's Syndrome ◽  
Small Cell ◽  
Prostatic Specific Antigen ◽  
Rare Tumour ◽  
Medical Treatments ◽  
Total Body

A 75-year-old man was hospitalized because of severe hypokalaemia due to ACTH dependent Cushing’s syndrome. Total body computed tomography (TBCT) and 68 Gallium DOTATATE PET/CT localized a voluminous prostate tumour. A subsequent transurethral prostate biopsy documented a small cell carcinoma positive for ACTH and calcitonin and negative for prostatic specific antigen (PSA) at immunocytochemical study; serum prostatic specific antigen (PSA) was normal. Despite medical treatments, Cushing’s syndrome was not controlled and the patient’s clinical condition progressively worsened. Surgical resection was excluded; the patient underwent a cycle of chemotherapy followed by febrile neutropenia and fatal intestinal perforation. This case report describes a rare case of Cushing’s syndrome and hypercalcitoninaemia due to a small cell carcinoma of the prostate, a rare tumour with very few therapeutic options and negative prognosis.

Cushing's syndrome with small cell carcinoma of the uterine cervix

1980 ◽  
Vol 69 (1) ◽  
pp. 140-144 ◽  
Author(s):  
Michael A. Lojek ◽  
Mehmet F. Fer ◽  
A.G. Kasselberg ◽  
Alan D. Glick ◽  
Lonnie S. Burnett ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Cushing’S Syndrome ◽  
Uterine Cervix ◽  
Cushing's Syndrome ◽  
Small Cell

scholarly journals Primary Small-Cell Carcinoma of the Palate with Cushing’s Syndrome: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Yingqiu Song ◽  
Zhenyu Lin ◽  
Lingjuan Chen ◽  
Gang Wu
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Cushing’S Syndrome ◽  
Neck Region ◽  
Cushing's Syndrome ◽  
Small Cell ◽  
First Case ◽  
Tender Mass ◽  
One Year

We report a 24-year-old woman presenting with a relapsed soy-bean-size tender mass at the junction of the soft and hard palate and a history of palatine tumor of small cell carcinoma. Reexcision surgery was performed and histopathological features were consistent. The patient was treated with six cycles of chemotherapy consisting of etoposide and cisplatin. After one year, the patient developed bone metastases and Cushing's syndrome, and successfully recovered with subsequent chemotherapy with irinotecan and cisplatin plus radiotherapy. There was no evidence of recurrence or metastasis for more than three years. Small cell carcinoma originating in the head and neck region has been reported to be highly aggressive and has a poor prognosis. This is the first case report of a patient with relapsed primary small cell carcinoma of the palate and successfully treated with second-line chemotherapy and local radiotherapy.

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