Macromolecular relaxation in the damped torsional oscillator and statistical segment models

Author(s):  
A. V. Tobolsky ◽  
D. B. DuPré

2018 ◽  
Vol 140 (2) ◽  
Author(s):  
Kevin D. Dorfman

The development of bright bisintercalating dyes for deoxyribonucleic acid (DNA) in the 1990s, most notably YOYO-1, revolutionized the field of polymer physics in the ensuing years. These dyes, in conjunction with modern molecular biology techniques, permit the facile observation of polymer dynamics via fluorescence microscopy and thus direct tests of different theories of polymer dynamics. At the same time, they have played a key role in advancing an emerging next-generation method known as genome mapping in nanochannels. The effect of intercalation on the bending energy of DNA as embodied by a change in its statistical segment length (or, alternatively, its persistence length) has been the subject of significant controversy. The precise value of the statistical segment length is critical for the proper interpretation of polymer physics experiments and controls the phenomena underlying the aforementioned genomics technology. In this perspective, we briefly review the model of DNA as a wormlike chain and a trio of methods (light scattering, optical or magnetic tweezers, and atomic force microscopy (AFM)) that have been used to determine the statistical segment length of DNA. We then outline the disagreement in the literature over the role of bisintercalation on the bending energy of DNA, and how a multiscale biomechanical approach could provide an important model for this scientifically and technologically relevant problem.



2006 ◽  
Author(s):  
Minoru Kubota ◽  
Muneyuki Fukuda ◽  
Toshiaki Obata ◽  
Yuji Ito ◽  
Andrey Penzev ◽  
...  


1990 ◽  
Vol 41 (10) ◽  
pp. 7167-7181 ◽  
Author(s):  
R. H. Torii ◽  
H. J. Maris ◽  
G. M. Seidel


1956 ◽  
Vol 34 (7) ◽  
pp. 643-652 ◽  
Author(s):  
P. G. Wilkinson

The absorption spectra of ethylene and ethylene-d4 have been investigated in the 1300 Å to 1500 Å region using the first order of a 21-ft. vacuum grating spectrograph. Vibrational constants for the v2(ag) stretching vibration and the v4(au) twisting vibration have been determined for each of the observed five Rydberg states. The torsional oscillator–rotator treatment has been applied to the observed twisting data, and potential barriers hindering free rotation of 500 to 1200 cm−1 were obtained. It is concluded that the stable equilibrium configuration of the Rydberg states is not of D2h symmetry but is probably bent or staggered.



2018 ◽  
Vol 88 (10) ◽  
pp. 1877-1891 ◽  
Author(s):  
Jialin Tian ◽  
Yinglin Yang ◽  
Liming Dai ◽  
Xiaoyue Lin


1985 ◽  
Vol 53 (12) ◽  
pp. 1192-1195
Author(s):  
Gauri Shanker ◽  
V. K. Gupta ◽  
B. Saraf ◽  
N. K. Sharma


1973 ◽  
Vol 29 (11) ◽  
pp. 2388-2392 ◽  
Author(s):  
R. Chidambaram ◽  
G. M. Brown


2017 ◽  
Vol 66 (6) ◽  
pp. 869-875
Author(s):  
Stanislav V Bushin ◽  
Marina A Bezrukova ◽  
Guy Koeckelberghs ◽  
André Persoons ◽  
Alexander V Yakimansky


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