An unreported polyether macrocyclic lactone with antioxidative and anti-lipoxygenase activities from the Babylonidae gastropod mollusc Babylonia spirata

2018 ◽  
Vol 27 (11-12) ◽  
pp. 2446-2453 ◽  
Author(s):  
Soumya Salas ◽  
Kajal Chakraborty
Keyword(s):  
Macrocyclic Lactone ◽  
Gastropod Mollusc

Histochemical survey of transmitters in the central ganglia of the gastropod mollusc Phestilla sibogae

2001 ◽  
Vol 305 (3) ◽  
pp. 417-432 ◽  
Author(s):  
Roger Croll ◽  
Dmitri Boudko ◽  
Michael Hadfield
Keyword(s):  
Gastropod Mollusc ◽  
Phestilla Sibogae

Types A and D Trichothecene Mycotoxins from the Fungus Myrothecium roridum

Planta Medica ◽  
2019 ◽  
Vol 85 (09/10) ◽  
pp. 774-780 ◽  
Author(s):  
Waranya Lakornwong ◽  
Kwanjai Kanokmedhakul ◽  
Kasem Soytong ◽  
Arm Unartngam ◽  
Sarawut Tontapha ◽  
...  
Keyword(s):  
Fungal Biomass ◽  
Macrocyclic Lactone ◽  
Antimalarial Activity ◽  
Pathogenic Fungus ◽  
The Other ◽  
Spectroscopic Methods ◽  
Type D ◽  
Vero Cell Line ◽  
Type A Trichothecenes ◽  
Myrothecium Roridum

AbstractChromatographic separation of extracts from the fungal biomass of a plant pathogenic fungus, Myrothecium roridum, yielded 8 trichothecene toxins including 6 type D trichothecenes (1–6) and 2 type A trichothecenes (7–8). 6′,12′-Epoxymyrotoxin A (1) and 7′-hydroxymytoxin B (2) were new macrocyclic trichothecenes, while the other trichothecenes were identified as myrotoxin B (3), myrotoxin D hydrate (4), 2′,3′-epoxymyrothecine A (5), miotoxin A (6), and 2 trichothecenes lacking the macrocyclic lactone system, roridin L-2 (7) and trichoverritone (8). The structures of these mycotoxins were characterized using spectroscopic methods. The absolute configurations of 1 and 2 were determined by NOESY and a comparison of their experimental and calculated ECD spectra. Most of these mycotoxins (1–4 and 6) exhibited highly potent antimalarial activity against Plasmodium falciparum. They also showed strong cytotoxicity towards KB and NCI-H187 cell lines (IC50 0.60 – 112.28 nM), as well as the Vero cell line (IC50 1.50 – 46.51 nM).

Stereocontrolled total synthesis of the macrocyclic lactone (−)-aspicilin

1987 ◽  
Vol 28 (21) ◽  
pp. 2409-2412 ◽  
Author(s):  
P.P. Waanders ◽  
L. Thijs ◽  
B. Zwanenburg
Keyword(s):  
Total Synthesis ◽  
Macrocyclic Lactone

ChemInform Abstract: A Novel Macrocyclic Lactone with Insecticidal Bioactivity from Streptomyces microflavus neau3.

ChemInform ◽  
2011 ◽  
Vol 43 (1) ◽  
pp. no-no
Author(s):  
Xiang-Jing Wang ◽  
Ji Zhang ◽  
Chong-Xi Liu ◽  
Dian-Liang Gong ◽  
Hui Zhang ◽  
...  
Keyword(s):  
Macrocyclic Lactone

A new macrocyclic lactone and a new quinoflavan from Celastrus hindsii

2014 ◽  
Vol 7 ◽  
pp. 169-172 ◽  
Author(s):  
Xian-Qing Hu ◽  
Wei Han ◽  
Zhu-Zhen Han ◽  
Qing-Xin Liu ◽  
Xi-Ke Xu ◽  
...  
Keyword(s):  
Macrocyclic Lactone
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