Long-Term Risk of In-Stent Restenosis and Stent Fracture for Extracranial Vertebral Artery Stenting

Stent implantation is widely used to treat blocked lumen. Stents were meshed structure made of polymers and metal alloys, including stainless steel, cobalt chrome and nitinol [1]. Clinical studies had demonstrated that stents helped to scaffold the diseased lesion up to one year when tissue adapted to the stented environment [2]. However, the permanently implanted stents inside artery were associated with complications such as stent fracture, tissue inflammation, in-stent restenosis and thrombosis [3]. Currently, biodegradable stents are attracting more attention due to its potential long-term efficacy in treating blocked lumens. The detailed characterizations of biodegradable stents are essential for the desired clinical outcomes.

Download Full-text

Stent fracture and restenosis after placement of a drug-eluting device in the vertebral artery origin and treatment with the stent-in-stent technique

Journal of Neurosurgery ◽

10.3171/jns.2007.106.5.907 ◽

2007 ◽

Vol 106 (5) ◽

pp. 907-911 ◽

Cited By ~ 23

Author(s):

Seong-Rim Kim ◽

Min-Woo Baik ◽

Seung-Hoon Yoo ◽

Ik-Seong Park ◽

Sang-Don Kim ◽

...

Keyword(s):

Vertebral Artery ◽

Stent Placement ◽

Coronary Stents ◽

Drug Eluting Stent ◽

Stent Fracture ◽

Stent Restenosis ◽

Stent Strut ◽

Drug Eluting ◽

In Stent Restenosis

✓ The authors report two cases of stent fracture and restenosis after placement of a drug-eluting device in the vertebral artery (VA) origin, and describe management of restenosis with the stent-in-stent technique. Two women, one 62 and the other 67 years of age, underwent stent placement in the VA origin to treat symptomatic and angiographically significant stenosis in this vessel. Sirolimus-eluting coronary stents (Cypher) were used in both cases. Four months after placement of the devices, the symptoms recurred. Follow-up angiography performed 5 months after insertion of the devices revealed a transverse stent fracture with separation of the fragments and severe in-stent restenosis in both cases. The restenoses were treated with reinsertion of coronary stents (Cypher and Jostent FlexMaster) by using the stent-in-stent technique. After stent reinsertion, the patients exhibited relief of symptoms. This paper is the first report of fracture in a drug-eluting stent and restenosis after stent placement in the VA origin. Restenosis caused by such a fracture can be managed successfully by performing the stent-in-stent maneuver. The physical properties of metallic devices, stent strut geometry, and anatomical peculiarities of the subclavian artery may be associated with stent fractures. Earlier follow-up angiography studies (within 6 months) are warranted.

Download Full-text

In-stent restenosis after vertebral artery stenting

International Journal of Cardiology ◽

10.1016/j.ijcard.2015.03.377 ◽

2015 ◽

Vol 187 ◽

pp. 430-433 ◽

Cited By ~ 9

Author(s):

Yongjun Jiang ◽

Xiaomeng Xu ◽

Zhuoyu Wen ◽

Xiaohui Xu ◽

Lian Yang ◽

...

Keyword(s):

Vertebral Artery ◽

Stent Restenosis ◽

Vertebral Artery Stenting ◽

In Stent Restenosis

Download Full-text

Stent Fracture and Occlusion after Treatment of Symptomatic Vertebral Artery Ostium Stenosis with a Self-Expanding Device

Interventional Neuroradiology ◽

10.15274/inr-2014-10068 ◽

2014 ◽

Vol 20 (6) ◽

pp. 755-760 ◽

Cited By ~ 1

Author(s):

Jun Lu ◽

Jiachun Liu ◽

Daming Wang ◽

Shuo Wang

Keyword(s):

Endovascular Treatment ◽

Vertebral Artery ◽

Treatment Modality ◽

Artery Stenosis ◽

Stent Fracture ◽

Endovascular Stenting ◽

Vertebral Artery Stenosis ◽

Stent Restenosis ◽

In Stent Restenosis

Endovascular stenting with a balloon expandable device is currently the preferred treatment modality for symptomatic proximal vertebral artery stenosis, but high rates of in-stent restenosis remain a major problem, for which stent fracture might be a contributing factor. Limited reports showed that placement of self-expanding stents in the proximal vertebral artery might reduce restenosis; no stent fracture has been reported to date. We describe here a new case of fracture and occlusion of a self-expanding stent after endovascular treatment of symptomatic vertebral artery ostium stenosis.

Download Full-text

Stent fracture in the brachiocephalic trunk

Vascular ◽

10.1177/1708538113478775 ◽

2013 ◽

Vol 21 (4) ◽

pp. 261-265 ◽

Cited By ~ 2

Author(s):

M Al-Natour ◽

A Renno ◽

M El-Fedaly ◽

J Abbas ◽

M Nazzal

Keyword(s):

English Literature ◽

The Body ◽

Stent Fracture ◽

Strongly Correlated ◽

Stent Restenosis ◽

Brachiocephalic Trunk ◽

Long Term Follow Up ◽

In Stent Restenosis

Stents are commonly used as a tool for revascularization of different vascular beds in the body. However, many pitfalls have been reported with their use, such as thrombosis, migration, restenosis or fractures. The latter have been strongly correlated to in-stent restenosis with long-term follow-up. We report a rare case of an early stent fracture in the brachiocephalic trunk with in-stent restenosis and recurrence of symptoms. To our knowledge there has been only one case report of a delayed brachiocephalic stent fracture in the English literature. We believe that our case is the first report of an early stent fracture in the brachiocephalic trunk.

Download Full-text