Direct porous structure generation of tissue engineering scaffolds for layer-based additive manufacturing

2015 ◽  
Vol 86 (1-4) ◽  
pp. 871-883 ◽  
Author(s):  
G. Papazetis ◽  
G.-C. Vosniakos
2019 ◽  
Vol 100 ◽  
pp. 631-644 ◽  
Author(s):  
Ana Paula Moreno Madrid ◽  
Sonia Mariel Vrech ◽  
María Alejandra Sanchez ◽  
Andrea Paola Rodriguez

2018 ◽  
Vol 9 ◽  
pp. 204173141880209 ◽  
Author(s):  
Patrick Rider ◽  
Željka Perić Kačarević ◽  
Said Alkildani ◽  
Sujith Retnasingh ◽  
Mike Barbeck

Bioprinting is the process of creating three-dimensional structures consisting of biomaterials, cells, and biomolecules. The current additive manufacturing techniques, inkjet-, extrusion-, and laser-based, create hydrogel structures for cellular encapsulation and support. The requirements for each technique, as well as the technical challenges of printing living cells, are discussed and compared. This review encompasses the current research of bioprinting for tissue engineering and its potential for creating tissue-mimicking structures.


RSC Advances ◽  
2016 ◽  
Vol 6 (84) ◽  
pp. 80522-80528 ◽  
Author(s):  
Xiao Lu ◽  
Yingjun Wang ◽  
Fangchun Jin

Pore and interconnection size are two key structural parameters for bone tissue engineering scaffolds.


2020 ◽  
Vol 05 (03) ◽  
pp. 2030002
Author(s):  
Chunze Yan ◽  
Gao Ma ◽  
Annan Chen ◽  
Ying Chen ◽  
Jiamin Wu ◽  
...  

Hydroxyapatite (HA) is a promising biomaterial for tissue engineering scaffolds due to its similar performance and composition to natural bone. However, the brittleness and poor toughness of pure HA limit its clinical application. Therefore, a lot of HA composites have been prepared to improve their mechanical performance. Fabricating complex and customized tissue engineering HA scaffolds have a very high requirement for manufacturing processes. It is difficult to fabricate ideal HA porous structures for artificial bone implants using traditional manufacturing processes, such as plasma spraying–sintering, and injection forming. Additive manufacturing (AM) could make three-dimensional physical parts with complex structures directly from computer-aided-design (CAD) models in a layer-by-layer way, and therefore show unique advantages in fabricating bone tissue engineering scaffolds with complex external shape and internal microporous structures. This paper reviews the state of the art for the preparation and AM process of HA and its composite materials, and raises the prospects for this research field.


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