scholarly journals Long-term thiazide use and risk of low-energy fractures among persons with Alzheimer’s disease—nested case-control study

2019 ◽  
Vol 30 (7) ◽  
pp. 1481-1489 ◽  
Author(s):  
H. Taipale ◽  
J. Rysä ◽  
J. Hukkanen ◽  
M. Koponen ◽  
A. Tanskanen ◽  
...  
2021 ◽  
Vol 10 (17) ◽  
pp. 3763
Author(s):  
Ji Hee Kim ◽  
Jae Keun Oh ◽  
Jee Hye Wee ◽  
Yoo Hwan Kim ◽  
Soo-Hwan Byun ◽  
...  

Background: Reports on the possible risks for Alzheimer’s disease (AD) have included tooth loss as a potential risk factor. However, there are few studies addressing the association between tooth loss and AD in a large sample of participants. Accordingly, the objective of the current study was to explore the association of tooth loss with the development of AD in Korean adults. Methods: This nested case–control study, which is an analysis utilizing the data of the Korean National Health Insurance Service Health Screening Cohort study, randomly selected AD and control participants among Korean residents aged ≥60 years. The association between the number of missing teeth and AD occurrence was examined using a logistic regression model. Participants’ lifestyle factors (smoking and alcohol consumption) and various medical conditions and comorbidities were included as covariates. Results: The mean number of missing teeth was 2.94 in the AD group and 2.59 in the control group. After adjusting for covariates, tooth loss was significantly associated with AD, with an odds ratio (OR) (per 16 missing teeth) of 1.15 (95% confidence interval (CI) = 1.07–1.23, p < 0.001). Conclusions: Tooth loss remained consistently significantly associated with an increased risk of AD for both upper and lower tooth loss. A higher number of missing teeth was related to a higher probability of AD occurrence in an elderly Korean population. Efforts to manage tooth loss could be a possible approach to prevent AD.


2018 ◽  
Vol 138 (2) ◽  
pp. 91-100 ◽  
Author(s):  
V. Tapiainen ◽  
H. Taipale ◽  
A. Tanskanen ◽  
J. Tiihonen ◽  
S. Hartikainen ◽  
...  

2016 ◽  
Vol 12 ◽  
pp. P1120-P1120
Author(s):  
Jin-Yi Hsu ◽  
Jen-Hung Wang ◽  
Ya-Ju Wu ◽  
Raymond Y. Lo

2012 ◽  
Vol 33 (1) ◽  
pp. 157-164 ◽  
Author(s):  
Eija Lönnroos ◽  
Pentti Kyyrönen ◽  
J. Simon Bell ◽  
Tischa J.M. van der Cammen ◽  
Sirpa Hartikainen

2018 ◽  
Vol 63 (2) ◽  
pp. 773-781 ◽  
Author(s):  
Jen-Hung Wang ◽  
Ya-Ju Wu ◽  
Boon Lead Tee ◽  
Raymond Y. Lo

2015 ◽  
Vol 11 (6) ◽  
pp. 587-592 ◽  
Author(s):  
Hugo Lövheim ◽  
Jonathan Gilthorpe ◽  
Anders Johansson ◽  
Sture Eriksson ◽  
Göran Hallmans ◽  
...  

2014 ◽  
Vol 24 ◽  
pp. S626
Author(s):  
S. Billioti de Gage ◽  
Y. Moride ◽  
T. Ducruet ◽  
T. Kurth ◽  
H. Verdoux ◽  
...  

2017 ◽  
Vol 56 (1) ◽  
pp. 119-128 ◽  
Author(s):  
Pasi Lampela ◽  
Anna-Maija Tolppanen ◽  
Antti Tanskanen ◽  
Jari Tiihonen ◽  
Sirpa Hartikainen ◽  
...  

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