scholarly journals Fracture risk following high-trauma versus low-trauma fracture: a registry-based cohort study

2020 ◽  
Vol 31 (6) ◽  
pp. 1059-1067 ◽  
Author(s):  
W. D. Leslie ◽  
J. T. Schousboe ◽  
S. N. Morin ◽  
P. Martineau ◽  
L. M. Lix ◽  
...  
Keyword(s):  
Cohort Study ◽  
Fracture Risk ◽  
Low Trauma Fracture

scholarly journals 493 Cohort study of osteoporosis and fracture risk: are we achieving benefit with secondary prevention?

2016 ◽  
Vol 22 (Suppl 2) ◽  
pp. A178.3-A178
Author(s):  
Llion Davies ◽  
Damon Berridge ◽  
Jane Lyons ◽  
Angharad Walters ◽  
Ronan A Lyons
Keyword(s):  
Cohort Study ◽  
Secondary Prevention ◽  
Fracture Risk

Fracture Risk in Living Kidney Donors: A Matched Cohort Study

2012 ◽  
Vol 59 (6) ◽  
pp. 770-776 ◽  
Author(s):  
Amit X. Garg ◽  
Jennie Pouget ◽  
Ann Young ◽  
Anjie Huang ◽  
Neil Boudville ◽  
...  
Keyword(s):  
Cohort Study ◽  
Fracture Risk ◽  
Matched Cohort ◽  
Kidney Donors ◽  
Living Kidney Donors ◽  
Matched Cohort Study

Number of Osteoporotic Sites and Fracture Risk Assessment: A Cohort Study From the Manitoba Bone Density Program

2006 ◽  
Vol 22 (3) ◽  
pp. 476-483 ◽  
Author(s):  
William D Leslie ◽  
James F Tsang ◽  
Patricia A Caetano ◽  
Lisa M Lix ◽  
Keyword(s):  
Risk Assessment ◽  
Cohort Study ◽  
Bone Density ◽  
Fracture Risk ◽  
Fracture Risk Assessment

Abstract TP160: Predicting Bone Fracture After Stroke—The Fracture Risk After Ischemic Stroke (FRAC-Stroke) Score

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Eric E Smith ◽  
Jiming Fang ◽  
Shabbir M Alibhai ◽  
Peter M Cram ◽  
Angela M Cheung ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Fracture Risk ◽  
Risk Score ◽  
Cumulative Incidence ◽  
Population Based ◽  
World Health ◽  
Stroke Severity ◽  
Stroke Patients ◽  
One Year ◽  
Low Trauma Fracture

Background: Risk for low trauma fracture is increased by >30% after ischemic stroke. Additionally, in the IRIS trial pioglitazone therapy prevented ischemic stroke but increased fracture risk. We derived a risk score to predict risk of fracture one year after ischemic stroke. Methods: The Fracture Risk after Ischemic Stroke (FRAC-Stroke) Score was derived in 20,435 ischemic stroke patients from the Ontario Stroke Registry discharged from 2003-2012, using Fine-Gray competing risk regression. Candidate variables were medical conditions included in the validated World Health Organization FRAX risk score complemented by variables related to stroke severity. Registry patients were linked to population-based Ontario health administrative data to identify low trauma fractures (defined as any fracture of the femur, forearm, humerus, pelvis or vertebrae, excluding fractures resulting from trauma, motor vehicle accidents, falls from a height or in people with active cancer). The score was externally validated in 13,698 other ischemic stroke patients in the population-based Ontario stroke audit (2002-2012). Results: Mean age was 72; 42% were women. Low trauma fracture occurred within 1 year of discharge in 741/20435 (3.6%); cumulative incidence increased linearly throughout follow-up. Age, discharge modified Rankin score (mRS), and history of arthritis, osteoporosis, falls and previous fracture contributed significantly to the model. Model discrimination was good (c statistic 0.72). Including discharge mRS significantly improved discrimination (relative integrated discrimination index 8.7%). Fracture risk was highest in patients with mRS 3 and 4 but lowest in bedbound patients (mRS 5). From the lowest to the highest FRAC-Stroke quintile the cumulative incidence of 1-year low trauma fracture increased from 1% to 9%. Predicted and observed rates of fracture were similar in the external validation cohort. Conclusion: The FRAC-Stroke score allows the clinician to identify ischemic stroke patients at higher risk of low trauma fracture within one year. This information might be used to target patients for early bone densitometry screening to diagnose and manage osteoporosis, and to estimate baseline risk prior to starting pioglitazone therapy.

scholarly journals Fracture risk assessment in celiac disease: a registry-based cohort study

2020 ◽  
Vol 32 (1) ◽  
pp. 93-99
Author(s):  
D.R. Duerksen ◽  
L.M. Lix ◽  
H. Johansson ◽  
E.V. McCloskey ◽  
N.C. Harvey ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Cohort Study ◽  
Celiac Disease ◽  
Fracture Risk ◽  
Fracture Risk Assessment

Fracture risk of patients suffering from dizziness: A retrospective cohort study

2010 ◽  
Vol 16 (4) ◽  
pp. 229-235 ◽  
Author(s):  
Carsten Kruschinski ◽  
Odile Sheehy ◽  
Eva Hummers-Pradier ◽  
Jacques Lelorier
Keyword(s):  
Cohort Study ◽  
Fracture Risk ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort
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