PARP1 protects from benzo[a]pyrene diol epoxide-induced replication stress and mutagenicity

Archives of Toxicology ◽

10.1007/s00204-017-2115-6 ◽

2017 ◽

Vol 92 (3) ◽

pp. 1323-1340 ◽

Author(s):

Jan M. F. Fischer ◽

Tabea Zubel ◽

Kirsten Jander ◽

Jelena Fix ◽

Irmela R. E. A. Trussina ◽

...

Keyword(s):

Replication Stress ◽

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Faculty Opinions recommendation of Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1161150.621622 ◽

2009 ◽

Author(s):

Jiri Lukas

Keyword(s):

Sister Chromatid ◽

Fragile Site ◽

Replication Stress

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Faculty Opinions recommendation of The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1163880.625910 ◽

2009 ◽

Author(s):

Michael Botchan

Keyword(s):

Replication Stress ◽

Cellular Sensitivity ◽

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Faculty Opinions recommendation of Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717982066.793472722 ◽

2013 ◽

Author(s):

Timothy Yen

Keyword(s):

Dna Replication ◽

Replication Stress ◽

Dna Replication Stress

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Faculty Opinions recommendation of Replication stress links structural and numerical cancer chromosomal instability.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717982163.793473215 ◽

2013 ◽

Author(s):

Timothy Yen ◽

Sanjeevani Arora

Keyword(s):

Chromosomal Instability ◽

Replication Stress

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Faculty Opinions recommendation of Cdc45 is a critical effector of myc-dependent DNA replication stress.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718007686.793476146 ◽

2013 ◽

Author(s):

David Cortez

Keyword(s):

Dna Replication ◽

Replication Stress ◽

Dna Replication Stress

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Faculty Opinions recommendation of Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718513256.793499379 ◽

2014 ◽

Author(s):

Maarten van Lohuizen ◽

Gaetano Gargiulo

Keyword(s):

Functional Decline ◽

Replication Stress ◽

Haematopoietic Stem Cells

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Faculty Opinions recommendation of tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725853978.793513437 ◽

2016 ◽

Author(s):

Lucio Comai

Keyword(s):

Replication Stress ◽

Trna Processing ◽

Processing Defects

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Faculty Opinions recommendation of MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727815151.793539951 ◽

2017 ◽

Author(s):

Mirit Aladjem ◽

Haiqing Fu

Keyword(s):

Stress Tolerance ◽

Chromosome Segregation ◽

Replication Stress ◽

Nuclease Activity

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Faculty Opinions recommendation of Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732721887.793543555 ◽

2018 ◽

Author(s):

Olivier Hyrien

Keyword(s):

Dna Replication ◽

Replication Stress ◽

Dna Replication Stress

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Faculty Opinions recommendation of 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.9007956.9704055 ◽

2011 ◽

Author(s):

Antony Carr

Keyword(s):

Replication Stress ◽

Dna Lesions ◽

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