Vascular large conductance calcium-activated potassium channels: Functional role and therapeutic potential

2007 ◽  
Vol 376 (3) ◽  
pp. 145-155 ◽  
Author(s):  
Birgit Eichhorn ◽  
Dobromir Dobrev
Keyword(s):  
Potassium Channels ◽  
Functional Role ◽  
Therapeutic Potential ◽  
Calcium Activated Potassium Channels

scholarly journals Small and Intermediate Calcium Activated Potassium Channels in the Heart: Role and Strategies in the Treatment of Cardiovascular Diseases

2020 ◽  
Vol 11 ◽  
Author(s):  
David Weisbrod
Keyword(s):  
Cardiovascular Diseases ◽  
Potassium Channels ◽  
Calcium Signaling ◽  
Intracellular Calcium ◽  
Functional Role ◽  
Physiological Role ◽  
Intracellular Calcium Signaling ◽  
Calcium Activated Potassium Channels

Calcium-activated potassium channels are a heterogeneous family of channels that, despite their different biophysical characteristics, structures, and pharmacological signatures, play a role of transducer between the ubiquitous intracellular calcium signaling and the electric variations of the membrane. Although this family of channels was extensively described in various excitable and non-excitable tissues, an increasing amount of evidences shows their functional role in the heart. This review aims to focus on the physiological role and the contribution of the small and intermediate calcium-activated potassium channels in cardiac pathologies.

scholarly journals Functional role of the β subunit of high conductance calcium-activated potassium channels

Neuron ◽  
1995 ◽  
Vol 14 (3) ◽  
pp. 645-650 ◽  
Author(s):  
Owen B McManus ◽  
Lisa M.H Helms ◽  
Leo Pallanck ◽  
Barry Ganetzky ◽  
Richard Swanson ◽  
...  
Keyword(s):  
Potassium Channels ◽  
Functional Role ◽  
Β Subunit ◽  
Calcium Activated Potassium Channels ◽  
High Conductance

[125I]Iberiotoxin-D19Y/Y36F, the First Selective, High Specific Activity Radioligand for High-Conductance Calcium-Activated Potassium Channels

Biochemistry ◽  
1997 ◽  
Vol 36 (7) ◽  
pp. 1943-1952 ◽  
Author(s):  
Alexandra Koschak ◽  
Robert O. Koch ◽  
Jessica Liu ◽  
Gregory J. Kaczorowski ◽  
Peter H. Reinhart ◽  
...  
Keyword(s):  
Potassium Channels ◽  
Specific Activity ◽  
High Specific Activity ◽  
Calcium Activated Potassium Channels ◽  
High Conductance

scholarly journals Down-regulation of the Small Conductance Calcium-activated Potassium Channels in Diabetic Mouse Atria

2015 ◽  
Vol 290 (11) ◽  
pp. 7016-7026 ◽  
Author(s):  
Fu Yi ◽  
Tian-You Ling ◽  
Tong Lu ◽  
Xiao-Li Wang ◽  
Jingchao Li ◽  
...  
Keyword(s):  
Potassium Channels ◽  
Diabetic Mouse ◽  
Down Regulation ◽  
Calcium Activated Potassium Channels ◽  
Small Conductance

Small-conductance calcium-activated potassium channels (SK3) are upregulated following denervation

2013 ◽  
Vol 30 ◽  
pp. 149-149
Author(s):  
C. Kramer ◽  
A. Kretschmer ◽  
C. Ertelt-Delbridge ◽  
M. Blobner ◽  
H. Fink
Keyword(s):  
Potassium Channels ◽  
Calcium Activated Potassium Channels ◽  
Small Conductance
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