Effects of 4,9-anhydrotetrodotoxin on voltage-gated Na+ channels of mouse vas deferens myocytes and recombinant NaV1.6 channels

2018 ◽  
Vol 391 (5) ◽  
pp. 489-499 ◽  
Author(s):  
Kohei Takahara ◽  
Tadashi Yamamoto ◽  
Keiichiro Uchida ◽  
Hai-Lei Zhu ◽  
Atsushi Shibata ◽  
...  
2012 ◽  
Vol 464 (5) ◽  
pp. 493-502 ◽  
Author(s):  
Noriyoshi Teramoto ◽  
Hai-Lei Zhu ◽  
Mari Yotsu-Yamashita ◽  
Tetsuichiro Inai ◽  
Thomas C. Cunnane

2008 ◽  
Vol 94 (8) ◽  
pp. 3340-3351 ◽  
Author(s):  
Hai-Lei Zhu ◽  
Manami Aishima ◽  
Hidetaka Morinaga ◽  
Richard D. Wassall ◽  
Atsushi Shibata ◽  
...  

1978 ◽  
Vol 28 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Tomio SEGAWA ◽  
Hiroko MURAKAMI ◽  
Hiroshi OGAWA ◽  
Haruaki YAJIMA

1990 ◽  
Vol 179 (1-2) ◽  
pp. 129-139 ◽  
Author(s):  
Frank Porreca ◽  
Diane LoPresti ◽  
Susan J. Ward

2005 ◽  
Vol 93 (5) ◽  
pp. 2787-2796 ◽  
Author(s):  
Y. Q. Lin ◽  
M. R. Bennett

Schwann cells, from a variety of sources, are known to possess P2Y purinergic metabotropic receptors. However, it is not known if Schwann cells associated with autonomic nerve terminals possess such receptors and if so whether these receptors are activated by the endogenous release of ATP from the nerve terminals. We show that such Schwann cells in the vas deferens give evoked calcium transients on nerve stimulation. These transients are mediated, at least in part, by the endogenous release of ATP, which acts on Schwann cell P2Y receptors to release calcium from within the cells. This work suggests the possibility that Schwann cells are active participants in the process of junctional transmission in the autonomic nervous system.


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