Study of self-assembly system of norfloxacin molecularly imprinted polymers based on simulated design

2021 ◽  
Vol 140 (1) ◽  
Author(s):  
Xiaoshuang Wang ◽  
Wensi Zhao ◽  
Junbo Liu ◽  
Shanshan Tang ◽  
Ruifa Jin
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Self Assembly ◽  
Assembly System ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

Facile one-step targeted immobilization of an enzyme based on silane emulsion self-assembled molecularly imprinted polymers for visual sensors

The Analyst ◽  
2020 ◽  
Vol 145 (1) ◽  
pp. 268-276 ◽  
Author(s):  
Guoning Chen ◽  
Hua Shu ◽  
Lu Wang ◽  
Kamran Bashir ◽  
Qun Wang ◽  
...  
Keyword(s):  
Crude Extract ◽  
Molecularly Imprinted Polymers ◽  
Self Assembly ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Step Process ◽  
Visual Sensors ◽  
One Step ◽  
Self Assembled

The silane emulsion self-assembly MIPs can specifically immobilize HRP in a one-step process from a crude extract of horseradish (unpurified samples).

scholarly journals Self-assembly Synthesis of Molecularly Imprinted Polymers for the Ultrasensitive Electrochemical Determination of Testosterone

Biosensors ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 16 ◽  
Author(s):  
Kai-Hsi Liu ◽  
Danny O’Hare ◽  
James L. Thomas ◽  
Han-Zhang Guo ◽  
Chien-Hsin Yang ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Self Assembly ◽  
Conductive Polymers ◽  
Limit Of Detection ◽  
Electrochemical Determination ◽  
Aromatic Rings ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Target Molecules ◽  
Metanilic Acid

Molecularly imprinted polymers (MIPs) can often bind target molecules with high selectivity and specificity. When used as MIPs, conductive polymers may have unique binding capabilities; they often contain aromatic rings and functional groups, which can undergo π-π and hydrogen bonding interactions with similarly structured target (or template) molecules. In this work, an electrochemical method was used to optimize the synthetic self-assembly of poly(aniline-co-metanilic acid) and testosterone, forming testosterone-imprinted electronically conductive polymers (TIECPs) on sensing electrodes. The linear sensing range for testosterone was from 0.1 to 100 pg/mL, and the limit of detection was as low as ~pM. Random urine samples were collected and diluted 1000-fold to measure testosterone concentration using the above TIECP sensors; results were compared with a commercial ARCHITECT ci 8200 system. The testosterone concentrations in the tested samples were in the range of 0.33 ± 0.09 to 9.13 ± 1.33 ng/mL. The mean accuracy of the TIECP-coated sensors was 90.3 ± 7.0%.

scholarly journals Self-assembly Synthesis of Molecularly Imprinted Polymers for the Ultrasensitive Electrochemical Determination of Testosterone

2020 ◽  
Author(s):  
Kai-Hsi Liu ◽  
Danny O’Hare ◽  
James L. Thomas James L. Thomas ◽  
Han-Zhang Guo ◽  
Chien-Hsin Yang ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Self Assembly ◽  
Limit Of Detection ◽  
Electrochemical Determination ◽  
Aromatic Rings ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Target Molecules ◽  
Metanilic Acid

Molecularly imprinted polymers (MIPs) can often bind target molecules with high selectivity and specificity. When used as MIPs, conductive polymers may have unique binding capabilities; they often contain aromatic rings, which have a great tendency to undergo covalent and hydrogen bonding interactions with similarly structured target (or template) molecules. In this work, an electrochemical method was used to optimize the synthetic self-assembly of poly(aniline-co-metanilic acid) and testosterone, forming testosterone-imprinted polymers (TIPs) on sensing electrodes. The linear sensing range for testosterone ranged from 0.1 to 100 pg/mL, and the limit of detection was as low as ~pM. Random urine samples were collected and diluted 1000 fold to measure testosterone concentration using the above TIP sensors in comparison with a commercial ARCHITECT ci 8200 system. The testosterone concentrations in the tested samples were in the range of 0.33± 0.09 to 9.13±1.33 ng/mL. The mean accuracy of the TIP-coated sensors was 90.3 ±7.0 %.

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