Human vision with a lesion of the parvocellular pathway: an optic neuritis model for selective contrast sensitivity deficits with severe loss of midget ganglion cell function

2011 ◽  
Vol 215 (3-4) ◽  
pp. 293-305 ◽  
Author(s):  
Amal M. Al-Hashmi ◽  
Daniel J. Kramer ◽  
Kathy T. Mullen
Keyword(s):  
Optic Neuritis ◽  
Ganglion Cell ◽  
Contrast Sensitivity ◽  
Cell Function ◽  
Human Vision ◽  
Parvocellular Pathway ◽  
Severe Loss

scholarly journals HE3286 Reduces Axonal Loss and Preserves Retinal Ganglion Cell Function in Experimental Optic Neuritis

2014 ◽  
Vol 55 (9) ◽  
pp. 5744 ◽  
Author(s):  
Reas S. Khan ◽  
Kimberly Dine ◽  
Esteban Luna ◽  
Clarence Ahlem ◽  
Kenneth S. Shindler
Keyword(s):  
Optic Neuritis ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Function ◽  
Axonal Loss ◽  
Retinal Ganglion ◽  
Retinal Ganglion Cell Function

Retinal ganglion cell function in recovered optic neuritis: Faster is not better

2018 ◽  
Vol 129 (9) ◽  
pp. 1813-1818 ◽  
Author(s):  
Pedro Monsalve ◽  
Sandy Ren ◽  
Hong Jiang ◽  
Jianhua Wang ◽  
Maja Kostic ◽  
...  
Keyword(s):  
Optic Neuritis ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Function ◽  
Retinal Ganglion ◽  
Retinal Ganglion Cell Function

Amacrine and ganglion cell contributions to the electroretinogram in amphibian retina

2001 ◽  
Vol 18 (1) ◽  
pp. 147-156 ◽  
Author(s):  
GAUTAM AWATRAMANI ◽  
JUE WANG ◽  
MALCOLM M. SLAUGHTER
Keyword(s):  
Contrast Agents ◽  
Ganglion Cell ◽  
Neuronal Activity ◽  
Opposite Effect ◽  
Cell Function ◽  
Ganglion Cells ◽  
Field Potential ◽  
Tiger Salamander ◽  
Third Order ◽  
Light Responses

The neuronal generators of the b- and d-waves of the electroretinogram (ERG) were investigated in the tiger salamander retina to determine if amacrine and ganglion cells contribute to this field potential. Several agents were used that affect third-order neurons, such as tetrodotoxin, baclofen, and NMDA agonists and antagonists. Baclofen, an agent that enhances light responses in third-order neurons, increased the d-wave and reduced the b-wave. In contrast, agents that decrease light responses in third-order neurons had the opposite effect of enhancing the b-wave and depressing the d-wave. The effect on the d-wave was particularly pronounced. The results indicate that third-order neuronal activity influences b- and d-waves of the ERG. The opposing actions suggest that the b-wave to d-wave ratio might serve as an measure of ganglion cell function.

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