scholarly journals The Photopic Negative Response: An Objective Measure of Retinal Ganglion Cell Function in Patients With Leber's Hereditary Optic Neuropathy

2017 ◽  
Vol 58 (6) ◽  
pp. BIO300 ◽  
Author(s):  
Rustum Karanjia ◽  
Adriana Berezovsky ◽  
Paula Yuri Sacai ◽  
Nivea Nunes Cavascan ◽  
Henry Yuheng Liu ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Neuropathy ◽  
Cell Function ◽  
Objective Measure ◽  
Negative Response ◽  
Photopic Negative Response ◽  
Retinal Ganglion ◽  
Retinal Ganglion Cell Function ◽  
Hereditary Optic Neuropathy

scholarly journals Citicoline in ophthalmologic practice: neuroprotection in ischemic optic neuropathy, diabetic retinopathy and amblyopia

2021 ◽  
Vol 9 (1) ◽  
pp. 28-33
Author(s):  
L.P. Novak ◽  
O.V. Tumanova
Keyword(s):  
Diabetic Retinopathy ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Optic Neuropathy ◽  
Cell Function ◽  
Patient Adherence ◽  
Ischemic Optic Neuropathy ◽  
Retinal Ganglion ◽  
Endogenous Dopamine ◽  
Retinal Ganglion Cell Function

Decrease and loss of vision are extremely important problems, quite common conditions that lead to disability. The most common causes are ischemic optic neuropathy, diabetic retinopathy, and amblyopia. The pathogenesis of these disea­ses is characterized by neurodegeneration, loss of structure and function of neurons. Citicoline may be considered for neuroprotection as the drug of choice in these clinical situations. Citicoline has antioxidant and anti-inflammatory properties, it reduces lipid peroxidation and the formation of free radicals, has anti-apoptotic and membrane-protective effects. The drug has a neuromodulatory effect and also contributes to the pre­servation of sphingomyelin, which ensures signal transmission in nerve cells. In ischemic optic neuropathy, oral citicoline can reduce nerve fiber loss and improve retinal ganglion cell function and visual tract function. In diabetic retinopathy, citicoline prevents synapse loss and improves macular and retinal ganglion cell function. In amblyopia, citicoline stimulates the function of neurotransmitters and neuromodulators, including an increase in the activity of endogenous dopamine and, at the same time, an improvement in the vascular aspects of neurological function. Axobrex is a convenient oral form of citicoline. With oral administration, the bioavailability of citicoline exceeds 90 %, Axobrex is non-toxic and very well-tolerated. The dosage regimen of Axobrex is simple, which contributes to satisfactory patient adherence to treatment. The use of Axobrex in patients with ischemic optic neuropathy, diabetic retinopathy, and amblyopia has an optimal balance of benefits and safety and is advisable for neuroprotection.

scholarly journals HE3286 Reduces Axonal Loss and Preserves Retinal Ganglion Cell Function in Experimental Optic Neuritis

2014 ◽  
Vol 55 (9) ◽  
pp. 5744 ◽  
Author(s):  
Reas S. Khan ◽  
Kimberly Dine ◽  
Esteban Luna ◽  
Clarence Ahlem ◽  
Kenneth S. Shindler
Keyword(s):  
Optic Neuritis ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Function ◽  
Axonal Loss ◽  
Retinal Ganglion ◽  
Retinal Ganglion Cell Function

scholarly journals Electrophysiological assessment of retinal ganglion cell function

2015 ◽  
Vol 141 ◽  
pp. 164-170 ◽  
Author(s):  
Vittorio Porciatti
Keyword(s):  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Function ◽  
Retinal Ganglion ◽  
Retinal Ganglion Cell Function

scholarly journals Correction: Pupillometry evaluation of melanopsin retinal ganglion cell function and sleep-wake activity in pre-symptomatic Alzheimer’s disease

PLoS ONE ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. e0230061
Author(s):  
Angela J. Oh ◽  
Giulia Amore ◽  
William Sultan ◽  
Samuel Asanad ◽  
Jason C. Park ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Function ◽  
Retinal Ganglion ◽  
Retinal Ganglion Cell Function

Loss of P retinal ganglion cell function in resolved optic neuritis

Neurology ◽  
1990 ◽  
Vol 40 (4) ◽  
pp. 649-649 ◽  
Author(s):  
M. Wall
Keyword(s):  
Optic Neuritis ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Function ◽  
Retinal Ganglion ◽  
Retinal Ganglion Cell Function

Growth hormone and retinal ganglion cell function: QNR/D cells as an experimental model

2014 ◽  
Vol 195 ◽  
pp. 183-189 ◽  
Author(s):  
Carlos Martínez-Moreno ◽  
Alexis Andres ◽  
Daniel Giterman ◽  
Edward Karpinski ◽  
Steve Harvey
Keyword(s):  
Growth Hormone ◽  
Ganglion Cell ◽  
Experimental Model ◽  
Retinal Ganglion Cell ◽  
Cell Function ◽  
Retinal Ganglion ◽  
D Cells ◽  
Retinal Ganglion Cell Function

scholarly journals Progressive Loss of Retinal Ganglion Cell Function Is Hindered with IOP-Lowering Treatment in Early Glaucoma

2012 ◽  
Vol 53 (2) ◽  
pp. 659 ◽  
Author(s):  
Lori M. Ventura ◽  
William J. Feuer ◽  
Vittorio Porciatti
Keyword(s):  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Function ◽  
Retinal Ganglion ◽  
Early Glaucoma ◽  
Progressive Loss ◽  
Retinal Ganglion Cell Function
Sign in / Sign up

Export Citation Format

Share Document