Short-Term Effects of TNF Inhibitors on Bone Turnover Markers and Bone Mineral Density in Rheumatoid Arthritis

2016 ◽  
Vol 98 (6) ◽  
pp. 580-585 ◽  
Author(s):  
Giovanni Orsolini ◽  
Giovanni Adami ◽  
Silvano Adami ◽  
Ombretta Viapiana ◽  
Luca Idolazzi ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Tnf Inhibitors ◽  
Mineral Density ◽  
Short Term ◽  
Turnover Markers ◽  
Short Term Effects

The study of bone mineral density and bone turnover markers in postmenopausal women with active rheumatoid arthritis

2005 ◽  
Vol 15 (6) ◽  
pp. 410-414 ◽  
Author(s):  
Shigeki Momohara ◽  
Hiroshi Okamoto ◽  
Toru Yago ◽  
Takefumi Furuya ◽  
Yuki Nanke ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Turnover ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Active Rheumatoid Arthritis ◽  
Mineral Density ◽  
Turnover Markers

scholarly journals Effects of denosumab on bone mineral density and bone turnover markers in rheumatoid arthritis patients switching from bisphosphonates

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Tetsuya Kaneko ◽  
Koichi Okamura ◽  
Yukio Yonemoto ◽  
Chisa Okura ◽  
Takahito Suto ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Mineral Density ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Mineral Density ◽  
Naive Group ◽  
Treatment Naïve ◽  
Turnover Markers ◽  
Switch Group

Abstract Background To compare the efficacy of 12-month denosumab treatment on bone mineral density (BMD) and bone turnover markers (BTMs) between treatment-naïve osteoporosis patients with rheumatoid arthritis (RA) and those with previous bisphosphonate (BP) therapy. Methods A total of 36 RA patients with osteoporosis completed 12-month follow-up. Twenty-five patients were osteoporotic treatment-naïve (naïve group), and 11 patients were previously treated with BPs (switch group) (average 7.9 years). BMD and BTMs were measured before and 6 and 12 months after treatment. Results BTM levels were higher in the naïve group at baseline. However, the same level of suppression was achieved at 6 months in both groups. Spine BMD increased significantly in both groups. There was no significant difference in the mean percent changes of BMD of the spine (naïve group: 6.8 ± 0.8, switch group: 5.1 ± 1.5), femoral neck (2.9 ± 1.4, 2.9 ± 1.3), and total hip (1.7 ± 0.9, 1.4 ± 1.1) between these two groups at 12 months. Conclusions The effects of denosumab on BMD and BTMs of the switch group after long-term BP treatment are comparable to those of the naïve group in RA patients. Thus, switching BPs to denosumab is one of the useful options to treat osteoporosis with RA.

High bone turnover markers and disturbances of bone mineral density in children with hypophosphataemic rickets

2017 ◽  
Author(s):  
Agnieszka Rusinska ◽  
Izabela Michalus ◽  
Izabela Woch ◽  
Paulina Adamiecka ◽  
Danuta Chlebna-Sokol
Keyword(s):  
Bone Mineral Density ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Mineral Density ◽  
Hypophosphataemic Rickets ◽  
High Bone Turnover ◽  
High Bone ◽  
Turnover Markers
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