Urinary Markers of Bone Turnover in Healthy Children and Adolescents: Age-Related Changes and Effect of Puberty

1998 ◽  
Vol 63 (5) ◽  
pp. 369-374 ◽  
Author(s):  
S. Mora ◽  
C. Prinster ◽  
M. C. Proverbio ◽  
A. Bellini ◽  
S. C. L. de Poli ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Children And Adolescents ◽  
Healthy Children ◽  
Urinary Markers ◽  
Age Related ◽  
Markers Of Bone Turnover ◽  
Age Related Changes

scholarly journals Age-Related Changes in Auditory Nogo-N200 Latency in Medication-Naïve Children and Adolescents with Attention-Deficit/Hyperactivity Disorder

2020 ◽  
Vol 17 (7) ◽  
pp. 702-709
Author(s):  
Yeon Jung Lee ◽  
Mi Young Jeong ◽  
Seoyoung Park ◽  
Jung Ho Kim ◽  
Ji-Sun Kim ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Children And Adolescents ◽  
Attention Deficit ◽  
Child Behavior Checklist ◽  
Rating Scale ◽  
Event Related Potential ◽  
Healthy Children ◽  
Hyperactivity Disorder ◽  
Age Related ◽  
Age Related Changes

Objective Event-related potential (ERP) changes with brain development in healthy children and adolescents. However, few studies have focused on age-related changes in the N200 and P300 components among individuals with attention-deficit/hyperactivity disorder (ADHD). Therefore, this study aimed to assess age-related differences in the auditory nogo-N200 components in individuals with ADHD.Methods We enrolled 46 participants with auditory nogo-N200 and nogo-P300 components. We assessed ADHD symptoms using the Advanced Test of Attention (ATA) and Korean ADHD Rating Scale-IV (K-ARS-IV). Moreover, we assessed emotional and behavioral problems using the Korean Child Behavior Checklist (K-CBCL). Further, we measured auditory ERPs.Results There were no differences with respect to sex or ATA, K-ARS-IV, and K-CBCL scores between the groups. With a 1-year increase in age, the nogo-N200 latency at Fz and Cz decreased by 6.08 ms and 4.88 ms, respectively; this result was statistically significant in multivariable linear regression adjusted by sex and dominant hand.Conclusion Our findings revealed age-related changes in nogo-N200 latency at the Fz and Cz electrodes in individuals with ADHD. Future studies should perform comparisons with healthy controls to determine whether auditory nogo-N200 can be used to evaluate the developmental level in individuals with ADHD.

scholarly journals Fear conditioning and stimulus generalization in association with age in children and adolescents

2021 ◽  
Author(s):  
Julia Reinhard ◽  
Anna Slyschak ◽  
Miriam A. Schiele ◽  
Marta Andreatta ◽  
Katharina Kneer ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Fear Conditioning ◽  
Repeated Measures ◽  
Conditioned Fear ◽  
Fear Learning ◽  
Stimulus Generalization ◽  
Healthy Children ◽  
Older Individuals ◽  
Age Related ◽  
Current Task

AbstractThe aim of the study was to investigate age-related differences in fear learning and generalization in healthy children and adolescents (n = 133), aged 8–17 years, using an aversive discriminative fear conditioning and generalization paradigm adapted from Lau et al. (2008). In the current task, participants underwent 24 trials of discriminative conditioning of two female faces with neutral facial expressions, with (CS+) or without (CS−) a 95-dB loud female scream, presented simultaneously with a fearful facial expression (US). The discriminative conditioning was followed by 72 generalization trials (12 CS+, 12 GS1, 12 GS2, 12 GS3, 12 GS4, and 12 CS−): four generalization stimuli depicting gradual morphs from CS+ to CS− in 20%-steps were created for the generalization phases. We hypothesized that generalization in children and adolescents is negatively correlated with age. The subjective ratings of valence, arousal, and US expectancy (the probability of an aversive noise following each stimulus), as well as skin conductance responses (SCRs) were measured. Repeated-measures ANOVAs on ratings and SCR amplitudes were calculated with the within-subject factors stimulus type (CS+, CS−, GS1-4) and phase (Pre-Acquisition, Acquisition 1, Acquisition 2, Generalization 1, Generalization 2). To analyze the modulatory role of age, we additionally calculated ANCOVAs considering age as covariate. Results indicated that (1) subjective and physiological responses were generally lower with increasing age irrespective to the stimulus quality, and (2) stimulus discrimination improved with increasing age paralleled by reduced overgeneralization in older individuals. Longitudinal follow-up studies are required to analyze fear generalization with regard to brain maturational aspects and clarify whether overgeneralization of conditioned fear promotes the development of anxiety disorders or vice versa.

Clinical utility of markers of bone turnover in children and adolescents

1998 ◽  
Vol 10 (4) ◽  
pp. 441-448 ◽  
Author(s):  
Christine M. de Ridder ◽  
Henriette A. Delemarre-van de Waal
Keyword(s):  
Bone Turnover ◽  
Children And Adolescents ◽  
Clinical Utility ◽  
Markers Of Bone Turnover

Age-related changes and reference intervals of RANKL, OPG, and bone turnover markers in Indian women

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Sandhya Nair ◽  
Sonam Hatkar ◽  
Anushree Patil ◽  
Suchitra Surve ◽  
Beena Joshi ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Bone Turnover Markers ◽  
Reference Intervals ◽  
Indian Women ◽  
Age Related ◽  
Turnover Markers ◽  
Age Related Changes

Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults

2004 ◽  
Vol 347 (1-2) ◽  
pp. 139-144 ◽  
Author(s):  
Michael V Miles ◽  
Paul S Horn ◽  
Peter H Tang ◽  
John A Morrison ◽  
Lili Miles ◽  
...  
Keyword(s):  
Coenzyme Q10 ◽  
Redox State ◽  
Healthy Children ◽  
Age Related ◽  
Age Related Changes ◽  
Apparently Healthy

Author response for "Decreased markers of bone turnover in children and adolescents with type 1 diabetes"

2019 ◽  
Author(s):  
Jens Otto Broby Madsen ◽  
Camilla Winther Herskin ◽  
Bo Zerahn ◽  
Niklas Rye Jørgensen ◽  
Birthe Susanne Olsen ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Bone Turnover ◽  
Children And Adolescents ◽  
Author Response ◽  
Markers Of Bone Turnover

scholarly journals Decreased markers of bone turnover in children and adolescents with type 1 diabetes

2020 ◽  
Vol 21 (3) ◽  
pp. 505-514 ◽  
Author(s):  
Jens Otto Broby Madsen ◽  
Camilla Winther Herskin ◽  
Bo Zerahn ◽  
Niklas Rye Jørgensen ◽  
Birthe Susanne Olsen ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Bone Turnover ◽  
Children And Adolescents ◽  
Markers Of Bone Turnover

Relationships between age-related biochemical markers of bone turnover and OPG, TGF-β1 and TGF-β2 in native Chinese women

2013 ◽  
Vol 39 (3) ◽  
pp. 105-114 ◽  
Author(s):  
Chao Chen ◽  
Meng-Ke Liang ◽  
Hong Zhang ◽  
Yi-Qun Peng ◽  
Xian-Ping Wu ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Biochemical Markers ◽  
Chinese Women ◽  
Age Related ◽  
Markers Of Bone Turnover ◽  
Tgf Β1
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