Mapping the Conduction System in Patients Undergoing Transcatheter Device Closure of Perimembranous Ventricular Septal Defect: A Proof-of-Concept Study

2021 ◽  
Author(s):  
Daljeet Kaur ◽  
Saileela Rajan ◽  
Mandar Shah ◽  
Nageswara Rao Koneti ◽  
Narasimhan Calambur
Keyword(s):  
Ventricular Septal Defect ◽  
Septal Defect ◽  
Conduction System ◽  
Proof Of Concept ◽  
Device Closure ◽  
Concept Study ◽  
Perimembranous Ventricular Septal Defect ◽  
Transcatheter Device

A meta-analysis of transcatheter device closure of perimembranous ventricular septal defect

2018 ◽  
Vol 254 ◽  
pp. 75-83 ◽  
Author(s):  
Haripriya Santhanam ◽  
LinQi Yang ◽  
Zhaojin Chen ◽  
Bee-Choo Tai ◽  
Dimple D. Rajgor ◽  
...  
Keyword(s):  
Ventricular Septal Defect ◽  
Septal Defect ◽  
Meta Analysis ◽  
Device Closure ◽  
Perimembranous Ventricular Septal Defect ◽  
Transcatheter Device

scholarly journals Transcatheter device closure of perimembranous ventricular septal defect in pediatric patients: Long-term outcomes

Heart Views ◽  
2020 ◽  
Vol 21 (1) ◽  
pp. 17
Author(s):  
JayalHasmukhbhai Shah ◽  
SanketPravinchandra Saraiya ◽  
TusharSudhakarrao Nikam ◽  
MukeshJitendra Jha
Keyword(s):  
Ventricular Septal Defect ◽  
Pediatric Patients ◽  
Septal Defect ◽  
Device Closure ◽  
Long Term Outcomes ◽  
Perimembranous Ventricular Septal Defect ◽  
Transcatheter Device

Transcatheter device closure of perimembranous ventricular septal defect in children treated with prophylactic oral steroids: acute and mid-term results of a single-centre, prospective, observational study

2015 ◽  
Vol 26 (4) ◽  
pp. 669-676 ◽  
Author(s):  
Bhavesh Thakkar ◽  
Nehal Patel ◽  
Shomu Bohora ◽  
Dharmin Bhalodiya ◽  
Tarandeep Singh ◽  
...  
Keyword(s):  
Ventricular Septal Defect ◽  
Heart Block ◽  
Septal Defect ◽  
Device Closure ◽  
Conduction Disturbances ◽  
Perimembranous Ventricular Septal Defect ◽  
Post Procedure ◽  
Oral Steroids ◽  
Transcatheter Device

AbstractBackground and ObjectiveAlthough transcatheter closure of perimembranous ventricular septal defect is emerging as an accepted, viable alternative, conduction disturbances still remain a major concern. Although steroid treatment has shown encouraging results with complete recovery, efficacy of prophylactic use of steroids is still speculative. We aim to study the mid-term outcome of perimembranous ventricular septal defect closure in children who received prophylactic oral steroids.Materials and methodsA prospective study was designed and antegrade device closure was attempted in eligible children who met the following inclusion criteria: age 3–18 years and weight >10 kg, defect diameter ⩽12 mm, and symptomatic, haemodynamic changes or history of infective endocarditis. Prophylactic steroid protocol consisted of 2 weeks oral prednisolone (1 mg/kg/day) initiated immediately after the procedure, and in the event of bradyarrhythmia it was escalated to 2 mg/kg. Patients were regularly followed-up at 1, 6, and 12 months and then annually. Patients with post-procedure heart block underwent Holter monitoring after a minimum of 1 year interval.ResultsBetween May, 2007 and August, 2012, successful device closure was accomplished in 290/297 patients. Mean age and weight were 9±3.12 years and 21±8.27 kg, respectively. The defect measured 5±1.38 mm on echocardiography. Mean fluoroscopy time was 12.98±8.64 minutes. Eight patients with major complications included one each with device embolisation, haemolysis, severe aortic regurgitation, and five with bradyarrhythmias, including complete atrioventricular block in three, Mobitz II in one, and bifascicular block in one. Patients with complete atrioventricular block responded to high-dose steroid and temporary pacemaker. Minor complications included post-procedure heart block (n=22) and blood loss (n=2). At 18.23±13.15 months follow-up, 8/27 (five major, 22 minor) with arrhythmia had persistent post-procedure heart block of no clinical consequences.ConclusionIn our patient population, transcatheter device closure of the perimembranous ventricular septal defect with prophylactic oral steroid resulted in excellent closure rate and acceptably low incidence of conduction disturbances at mid-term follow-up.

Complete atrio-ventricular heart block, a not to be forgotten complication in transcatheter closure of perimembranous ventricular septal defect – a case report and review of literature

2021 ◽  
pp. 1-4
Author(s):  
Ming Chern Leong ◽  
Mazeni Alwi
Keyword(s):  
Ventricular Septal Defect ◽  
Heart Block ◽  
Septal Defect ◽  
Transcatheter Closure ◽  
Review Of Literature ◽  
Device Closure ◽  
Bundle Branch Block ◽  
Know How ◽  
Perimembranous Ventricular Septal Defect ◽  
New Onset

Abstract Device occlusion of perimembranous ventricular septal defect is gaining popularity with the emergence of newer, softer occluders and improved technical know-how. We report a 26-year-old lady with a moderate size perimembranous ventricular septal defect who had a new onset of bundle branch block shortly after device closure. The patient subsequently developed a complete atrio-ventricular heart block.

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