Human Helios, an Ikaros -related zinc finger DNA binding protein: cDNA cloning and tissue expression pattern

1999 ◽  
Vol 50 (1-2) ◽  
pp. 106-108 ◽  
Author(s):  
Y. Hosokawa ◽  
Yumiko Maeda ◽  
Masao Seto
Genomics ◽  
1999 ◽  
Vol 61 (3) ◽  
pp. 326-329 ◽  
Author(s):  
Yoshitaka Hosokawa ◽  
Yumiko Maeda ◽  
Ei-ichi Takahashi ◽  
Mikio Suzuki ◽  
Masao Seto

1991 ◽  
Vol 11 (5) ◽  
pp. 2665-2674 ◽  
Author(s):  
A S Perkins ◽  
R Fishel ◽  
N A Jenkins ◽  
N G Copeland

Evi-1 was originally identified as a common site of viral integration in murine myeloid tumors. Evi-1 encodes a 120-kDa polypeptide containing 10 zinc finger motifs located in two domains 380 amino acids apart and an acidic domain located carboxy terminal to the second set of zinc fingers. These features suggest that Evi-1 is a site-specific DNA-binding protein involved in the regulation of RNA transcription. We have purified Evi-1 protein from E. coli and have employed a gel shift-polymerase chain reaction method using random oligonucleotides to identify a high-affinity binding site for Evi-1. The consensus sequence for this binding site is TGACAAGATAA. Evi-1 protein specifically protects this motif from DNase I digestion. By searching the nucleotide sequence data bases, we have found this binding site both in sequences 5' to genes in putative or known regulatory regions and within intron sequences.


FEBS Letters ◽  
1993 ◽  
Vol 321 (2-3) ◽  
pp. 233-236 ◽  
Author(s):  
Gina Pengue ◽  
Paola Cannada-Bartoli ◽  
Luigi Lania

PLoS ONE ◽  
2013 ◽  
Vol 8 (1) ◽  
pp. e52908 ◽  
Author(s):  
Florence Guillière ◽  
Chloé Danioux ◽  
Carole Jaubert ◽  
Nicole Desnoues ◽  
Muriel Delepierre ◽  
...  

2010 ◽  
Vol 44 (2) ◽  
pp. 233-244 ◽  
Author(s):  
N. A. Zhigalova ◽  
S. V. Zhenilo ◽  
D. S. Aithozhina ◽  
E. B. Prokhortchouk

1991 ◽  
Vol 19 (19) ◽  
pp. 5117-5123 ◽  
Author(s):  
Jaime F. Angulo ◽  
Evelyne Rouer ◽  
Alexander Mazin ◽  
Marie-geneviève Mattei ◽  
Agnèves Tissier ◽  
...  

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