Functional analysis and chromosomal mapping of Gata5 , a gene encoding a zinc finger DNA-binding protein

1999 ◽  
Vol 10 (10) ◽  
pp. 993-999 ◽  
Author(s):  
Georges Nemer ◽  
Salman T. Qureshi †, ‡ , Daniell
Genomics ◽  
1999 ◽  
Vol 61 (3) ◽  
pp. 326-329 ◽  
Author(s):  
Yoshitaka Hosokawa ◽  
Yumiko Maeda ◽  
Ei-ichi Takahashi ◽  
Mikio Suzuki ◽  
Masao Seto

Genomics ◽  
1992 ◽  
Vol 13 (3) ◽  
pp. 658-664 ◽  
Author(s):  
Ching Li ◽  
Aldons J. Lusis ◽  
Robert Sparkes ◽  
Sanh-Moc Tran ◽  
Richard Gaynor

Genomics ◽  
1992 ◽  
Vol 13 (3) ◽  
pp. 665-671 ◽  
Author(s):  
Ching Li ◽  
Aldons J. Lusis ◽  
Robert Sparkes ◽  
Ajay Nirula ◽  
Richard Gaynor

1991 ◽  
Vol 11 (5) ◽  
pp. 2665-2674 ◽  
Author(s):  
A S Perkins ◽  
R Fishel ◽  
N A Jenkins ◽  
N G Copeland

Evi-1 was originally identified as a common site of viral integration in murine myeloid tumors. Evi-1 encodes a 120-kDa polypeptide containing 10 zinc finger motifs located in two domains 380 amino acids apart and an acidic domain located carboxy terminal to the second set of zinc fingers. These features suggest that Evi-1 is a site-specific DNA-binding protein involved in the regulation of RNA transcription. We have purified Evi-1 protein from E. coli and have employed a gel shift-polymerase chain reaction method using random oligonucleotides to identify a high-affinity binding site for Evi-1. The consensus sequence for this binding site is TGACAAGATAA. Evi-1 protein specifically protects this motif from DNase I digestion. By searching the nucleotide sequence data bases, we have found this binding site both in sequences 5' to genes in putative or known regulatory regions and within intron sequences.


1991 ◽  
Vol 230 (1-2) ◽  
pp. 332-336 ◽  
Author(s):  
Hisami Yamada ◽  
Takayuki Yoshida ◽  
Ken-ichi Tanaka ◽  
Chihiro Sasakawa ◽  
Takeshi Mizuno

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