Primary cutaneous Ewing’s sarcoma/primitive neuroectodermal tumor manifesting numerous small and huge ulcerated masses: its complete remission by chemotherapy and magnetic resonance imaging findings

2010 ◽  
Vol 39 (6) ◽  
pp. 595-600 ◽  
Author(s):  
Won-Jong Bahk ◽  
Eun-Deok Chang ◽  
Jung Min Bae ◽  
Kyung-Ah Chun ◽  
An-Hee Lee ◽  
...  
2013 ◽  
Vol 7 (5-6) ◽  
Author(s):  
Tao Wu ◽  
Tao Jin ◽  
Deyi Luo ◽  
Lin Chen ◽  
Xiang Li

We present a case of Ewing’s sarcoma (ES) and primitive neuroectodermal tumor (PNET) of prostate. A 29-year-old male presented with difficult defecation and anus distention and was found on magnetic resonance imaging (MRI) scan of the pelvis to have a prostate tumor. A transrectal ultrasound guided needle biopsy confirmed the diagnosis. The patient underwent cystoprostatectomy and replacement ileocystoplasty and was followed by multiagent chemotherapy. PNET/EWS of the prostate is an extremely rare neoplasm. And the prognosis is very poor, so we should pay enough attention to the differential diagnosis and treatment.


2017 ◽  
Vol 3 (3) ◽  
Author(s):  
Muhammad Bilal Fayyaz ◽  
Imran Khalid Niazi ◽  
Amjad Iqbal

Purpose: Ewing’s family tumour is an extremely rare tumour, with annual incidence rates amongst Caucasian children <21 years being in the range of 2–3 cases per million in the U.S. There are mainly three subtypes including Ewing’s sarcoma (ES) of bone, extraosseous (EO) Ewing’s tumour and Peripheral primitive neuroectodermal tumour. Although extremely rare, this study represents a review of various types of cases and the significance of imaging including its baseline and post-treatment response radiological characteristics. There are a very few cases of EO ES in the current literature with variable spectrum of tumour site and their imaging characteristics.Materials and Methods: Electronic records were retrospectively reviewed from 1 May 2011 to 1 May 2016 with patients who were diagnosed as histologically proven ES. A number of patients, gender and base line computed tomography (CT)/magnetic resonance imaging findings for staging were reviewed.Results: A total of 568 patients with diagnosed ES were analysed, of which 15 patients had EO type of ES. Of these only 8 patients had baseline imaging available which included tumours arising from the occipital region, orbit, anterior mediastinum, anterior abdominal wall, mesentery, kidney, prostate gland and presacral region.Conclusion: EO ES is a rare entity and can involve a wide array of soft tissue organs. A cross-sectional imaging with CT and MR has a key role in pre- and post-treatment assessment.Key words: Computed tomography, Ewing’s sarcoma, extraosseous Ewing’s, magnetic resonance imaging, peripheral primitive neuroectodermal tumour


1999 ◽  
Vol 17 (10) ◽  
pp. 3234-3237 ◽  
Author(s):  
Maryam Fouladi ◽  
Amar Gajjar ◽  
James M. Boyett ◽  
Andrew W. Walter ◽  
Stephen J. Thompson ◽  
...  

PURPOSE: Leptomeningeal disease (LMD) significantly affects the prognosis and treatment of pediatric patients with medulloblastoma or primitive neuroectodermal tumor (PNET). Examination of CSF for malignant cells, detection of LMD on spinal magnetic resonance imaging (MRI), or both are the methods routinely used to diagnose LMD. A recent study suggested 100% correlation between CSF and MRI findings in children with medulloblastoma. To determine the validity of this hypothesis, we compared the rate of detection of LMD between concurrent lumbar CSF cytology and spinal MRI performed at diagnosis in patients with medulloblastoma or PNET. PATIENTS AND METHODS: As a part of diagnostic staging, 106 consecutive patients newly diagnosed with medulloblastoma or PNET were evaluated with concurrent lumbar CSF cytology and spinal MRI. CSF cytology was examined for the presence of malignant cells and spinal MRI was reviewed independently for the presence of LMD. RESULTS: Thirty-four patients (32%) were diagnosed with LMD based on CSF cytology, spinal MRI, or both. There were 21 discordant results. Nine patients (8.5%) with positive MRI had negative CSF cytology. Twelve patients (11.3%) with positive CSF cytology had negative MRIs. The exact 95% upper bounds on the proportion of patients with LMD whose disease would have gone undetected using either CSF cytology or MRI as the only diagnostic modality were calculated at 14.4% and 17.7%, respectively. CONCLUSION: With the use of either CSF cytology or spinal MRI alone, LMD would be missed in up to 14% to 18% of patients with medulloblastoma or PNET. Thus, both CSF cytology and spinal MRI should routinely be used to diagnose LMD in patients with medulloblastoma or PNET.


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