Ewing’s sarcoma/primitive neuroectodermal tumor of the prostate a case report and literature review

2013 ◽  
Vol 7 (5-6) ◽  
Author(s):  
Tao Wu ◽  
Tao Jin ◽  
Deyi Luo ◽  
Lin Chen ◽  
Xiang Li

We present a case of Ewing’s sarcoma (ES) and primitive neuroectodermal tumor (PNET) of prostate. A 29-year-old male presented with difficult defecation and anus distention and was found on magnetic resonance imaging (MRI) scan of the pelvis to have a prostate tumor. A transrectal ultrasound guided needle biopsy confirmed the diagnosis. The patient underwent cystoprostatectomy and replacement ileocystoplasty and was followed by multiagent chemotherapy. PNET/EWS of the prostate is an extremely rare neoplasm. And the prognosis is very poor, so we should pay enough attention to the differential diagnosis and treatment.

2013 ◽  
Vol 7 (5-6) ◽  
pp. 458 ◽  
Author(s):  
Tao Wu ◽  
Tao Jin ◽  
Deyi Luo ◽  
Lin Chen ◽  
Xiang Li

We present a case of Ewing’s sarcoma and primitive neuroectodermal tumour (PNET) of the prostate. A 29-year-old male presented with difficult defecation and anus distention; on magnetic resonance imaging scan of the pelvis, we found a prostate tumour. A transrectal ultrasound-guided needle biopsy confirmed the diagnosis. The patient underwent cystoprostatectomy and replacement ileocystoplasty and was followed by multi-agent chemotherapy. PNET/ Ewing’s sarcoma of the prostate is extremely rare. The prognosis is very poor, so we should pay enough attention to the differential diagnosis and treatment.


2021 ◽  
Vol 5 (3) ◽  
pp. 358
Author(s):  
Kanika Singh ◽  
Sujata Raychaudhuri ◽  
Varsha Chauhan ◽  
Akanksha Bajaj ◽  
Reetika Menia

A primitive neuroectodermal tumor (PNET) is a rare entity occurring most commonly in the 2nd and 3rd decade and is very rare in patients over 40 years of age. PNET is a round cell malignancy of presumably primitive neuroectodermal tissue or migratory neural crest cells arising from soft tissue or bone. PNET occurring outside the central nervous system is called peripheral PNET (p PNET) and most commonly involves the trunk and extremities Here we present a case of PNET diagnosed in an elderly male who presented with a soft tissue mass in the gluteal region. The histopathology with ancillary techniques including immunohistochemistry and molecular studies helped in establishing the diagnosis of PNET. They are characterized by translocation leading to the fusion of Ewing’s Sarcoma (EWS) gene on 22q12 with any of the member of the ETS (E 26 transformation specific or E -twenty – six) family of transcription factors with the most frequent being t (11;22) (q24;12). Intensive multiagent chemotherapy is the mainstay of treatment as it has great potential for metastatic spread. The prognosis of adults with Ewing’s sarcoma (ES)/PNET is not well known, however, some reports suggested that adults with ES/PNET have a poorer prognosis than children. Cytology is the first line of diagnosis for RCT. However, the type-specific diagnosis or final diagnosis of p PNET is based on histopathology aided with IHC and other ancillary techniques.International Journal of Human and Health Sciences Vol. 05 No. 03 July’21 Page: 358-361


2016 ◽  
Vol 97 (3) ◽  
pp. 365-368 ◽  
Author(s):  
Yinghui Ding ◽  
Zhenlin Huang ◽  
Yafei Ding ◽  
Zhankui Jia ◽  
Chaohui Gu ◽  
...  

Author(s):  
Izabela S. Alves ◽  
Luiz G. Berriel ◽  
Rafael T. Alves ◽  
Mateus O. Potratz ◽  
Marcele B. Pinto ◽  
...  

2007 ◽  
Vol 22 (Suppl) ◽  
pp. S159 ◽  
Author(s):  
Yoon Young Lee ◽  
Do Hoon Kim ◽  
Ji Hye Lee ◽  
Jong Sang Choi ◽  
Kwang Ho In ◽  
...  

2018 ◽  
Vol 35 (6) ◽  
pp. 885-888 ◽  
Author(s):  
Suraj K. Kulkarni ◽  
Nagaraj Moorthy ◽  
Shankar Somanna ◽  
Manjunath Cholenahally Nanjappa

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