Anal fistula at roof of ischiorectal fossa inside levator-ani muscle (RIFIL): a new highly complex anal fistula diagnosed on MRI

Author(s):  
Pankaj Garg ◽  
Sushil Dawka ◽  
Vipul D. Yagnik ◽  
Baljit Kaur ◽  
Geetha R. Menon
2021 ◽  
pp. 1-4
Author(s):  
Avanish Saklani ◽  
Seke Manase Ephraim KAZUMA ◽  
Mufaddal Kazi ◽  
Vivek Sukumar ◽  
Avanish Saklani

Soft Tissue Sarcomas (STS) are rare malignant tumors that: arise from mesenchyme, 80% arise in soft tissue while 20% in bone, and they comprise 1% adult tumors. Gluteus maximus STS is site with frequently diagnoses of high- and low-grade STS. Low-grade STS respond well to surgery alone while high-grade STS require preoperative chemoradiation therapy, followed by surgery, and then postoperative chemotherapy. Work-up includes: a core needle biopsy for histopathological diagnosis, MRI for imaging of local disease and Contrast enhanced CT scan for pulmonary metastasis. Recurrence is viewed as a sign of poor local treatment and a risk for distant metastasis. Reduction of local recurrence does not lead to improved survival, but lack of disease progression with pulmonary metastasis does. In our patient, laparoscopy allowed total mesorectal excision dissection and sparing of rectum, as there was no metastatic spread of tumor to the rectum. Despite excision of right levator ani muscle, our patient maintained her continence, as shown by Fucini et al. [1] that continence would be maintained despite dissection and separation of levator ani muscle from the anal complex unit (external and internal anal sphincter) followed by unilateral excision of levator ani muscle, while achieving good oncologic and anal function outcome. We present our management of a 55-year-old lady with recurrent gluteal STS with extension into the ischiorectal fossa managed at Tata Memorial Hospital, in Parel, Mumbai, India, in the Department of Colorectal Surgery.


Author(s):  
Marina Gabriela M. C. Mori da Cunha ◽  
Katerina Mackova ◽  
Lucie Hajkova Hympanova ◽  
Maria Augusta T. Bortolini ◽  
Jan Deprest

Abstract Introduction and hypothesis We aimed to summarize the knowledge on the pathogenesis of pelvic organ prolapse (POP) generated in animal models. Methods We searched MEDLINE, Embase, Cochrane and the Web of Science to establish what animal models are used in the study of suggested risk factors for the development of POP, including pregnancy, labor, delivery, parity, aging and menopause. Lack of methodologic uniformity precluded meta-analysis; hence, results are presented as a narrative review. Results A total of 7426 studies were identified, of which 51 were included in the analysis. Pregnancy has a measurable and consistent effect across species. In rats, simulated vaginal delivery induces structural changes in the pelvic floor, without complete recovery of the vaginal muscular layer and its microvasculature, though it does not induce POP. In sheep, first vaginal delivery has a measurable effect on vaginal compliance; measured effects of additional deliveries are inconsistent. Squirrel monkeys can develop POP. Denervation of their levator ani muscle facilitates this process in animals that delivered vaginally. The models used do not develop spontaneous menopause, so it is induced by ovariectomy. Effects of menopause depend on the age at ovariectomy and the interval to measurement. In several species menopause is associated with an increase in collagen content in the longer term. In rodents there were no measurable effects of age apart of elastin changes. We found no usable data for other species. Conclusion In several species there are measurable effects of pregnancy, delivery and iatrogenic menopause. Squirrel monkeys can develop spontaneous prolapse.


2020 ◽  
Vol 90 (12) ◽  
pp. 2593-2593
Author(s):  
Johannes Jongen ◽  
Jessica Schneider ◽  
Tilman Laubert ◽  
Volker Kahlke

2021 ◽  
Author(s):  
Natalia Uribe ◽  
Zutoia Balciscueta ◽  
M. Carmen Martín ◽  
Janine Tabet ◽  
Manuel López

Sign in / Sign up

Export Citation Format

Share Document