scholarly journals Blood perfusion and bone formation before and after minimally invasive periacetabular osteotomy analysed by Positron Emission Tomography combined with Computed Tomography

2013 ◽  
Vol 37 (5) ◽  
pp. 789-794
Author(s):  
Inger Mechlenburg ◽  
Flemming Hermansen ◽  
Theis Thillemann ◽  
Kjeld Søballe
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Bone Formation ◽  
Minimally Invasive ◽  
Periacetabular Osteotomy ◽  
Blood Perfusion ◽  
Emission Tomography ◽  
Positron Emission ◽  
Before And After

Positron Emission Tomography with 11C-Methionine and Computed Tomography of Intracranial Tumours Compared with Histopathologic Examination of Multiple Biopsies

1987 ◽  
Vol 28 (6) ◽  
pp. 673-681 ◽  
Author(s):  
M. Mosskin ◽  
H. von Holst ◽  
M. Bergström ◽  
V. P. Collins ◽  
L. Eriksson ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Contrast Medium ◽  
Mass Effect ◽  
Tumour Cells ◽  
Emission Tomography ◽  
Normal Brain ◽  
Positron Emission ◽  
Multiple Biopsies ◽  
Before And After

A selected group of 36 patients with suspected supratentorial gliomas were investigated with positron emission tomography (PET) using 11C-methionine and transmission computed tomography (CT) before and after intravenous injection of contrast medium. Every examination was performed with the head fixed in a plastic helmet and a baseplate to guarantee that the slice orientation was the same at examinations with the two modalities and over time. Guided by the examinations, multiple stereotactic biopsies were performed with the biopsy instrument mounted on the baseplate. Regional accumulation of methionine was compared with histology of the corresponding samples and with attenuation before and after injection of contrast medium as well as mass effect on CT. Typically, there was a low attenuating lesion with a slight mass effect on CT. There was an increased accumulation compared with normal brain tissue in 31 cases of tumours and ordinary or decreased accumulation in 3 cases of tumours. In 22 cases with increased accumulation of methionine the extension of the tumour judged by PET corresponded with that of histology. In 4 cases tumour cells were found outside the area with pathologic methionine uptake. In 5 patients there were areas with increased methionine accumulation where no tumour cells were found. In 22 cases PET using methionine was more accurate than CT in defining the tumour boundaries as determined from the histologic findings. Four groups of biopsy specimens with different amounts of methionine accumulation are described. The uptake in a single biopsy gives good but not exact information about the histology of the specimen.

scholarly journals The EANM practice guidelines for parathyroid imaging

2021 ◽  
Author(s):  
Petra Petranović Ovčariček ◽  
Luca Giovanella ◽  
Ignasi Carrió Gasset ◽  
Elif Hindié ◽  
Martin W. Huellner ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Nuclear Medicine ◽  
Minimally Invasive ◽  
Minimally Invasive Parathyroidectomy ◽  
Parathyroid Glands ◽  
Emission Tomography ◽  
Invasive Parathyroidectomy ◽  
Positron Emission ◽  
Parathyroid Imaging

Abstract Introduction Nuclear medicine parathyroid imaging is important in the identification of hyperfunctioning parathyroid glands in primary hyperparathyroidism (pHPT), but it may be also valuable before surgical treatment in secondary hyperparathyroidism (sHPT). Parathyroid radionuclide imaging with scintigraphy or positron emission tomography (PET) is a highly sensitive procedure for the assessment of the presence and number of hyperfunctioning parathyroid glands, located either at typical sites or ectopically. The treatment of pHPT is mostly directed toward minimally invasive parathyroidectomy, especially in cases with a single adenoma. In experienced hands, successful surgery depends mainly on the exact preoperative localization of one or more hyperfunctioning parathyroid adenomas. Failure to preoperatively identify the hyperfunctioning parathyroid gland challenges minimally invasive parathyroidectomy and might require bilateral open neck exploration. Methods Over a decade has now passed since the European Association of Nuclear Medicine (EANM) issued the first edition of the guideline on parathyroid imaging, and a number of new insights and techniques have been developed since. The aim of the present document is to provide state-of-the-art guidelines for nuclear medicine physicians performing parathyroid scintigraphy, single-photon emission computed tomography/computed tomography (SPECT/CT), positron emission tomography/computed tomography (PET/CT), and positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with pHPT, as well as in those with sHPT. Conclusion These guidelines are written and authorized by the EANM to promote optimal parathyroid imaging. They will assist nuclear medicine physicians in the detection and correct localization of hyperfunctioning parathyroid lesions.

Targeted Minimally Invasive Parathyroidectomy for Ectopic Aortopulmonary Adenoma under Gamma Probe Guidance

2018 ◽  
Vol 13 (6) ◽  
pp. 451-454
Author(s):  
Defne Güneş Ergi ◽  
Ilknur Kepenekci Bayram ◽  
Cagdas Baran ◽  
Elgin Özkan ◽  
Mustafa Bahadir Inan ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Parathyroid Hormone ◽  
Minimally Invasive ◽  
Reference Range ◽  
Gamma Probe ◽  
Emission Tomography ◽  
Aberrant Right Subclavian Artery ◽  
Aortopulmonary Window ◽  
Positron Emission

We report a case of 53-year-old woman with the parathyroid adenoma (PA) located in the aortopulmonary window with an aberrant right subclavian artery. Her preoperative calcium level was 11.3 mg/dL (reference range = 8.8–10.6 mg/dL). The parathyroid hormone level was significantly elevated at 127.4 pg/mL (reference range = 12–88 pg/mL) as measured on immunoradiometric assay. Dual-phase technetium-99m–labeled sestamibi parathyroid scintigraphy and fluorine-18 18F-fluorocholine positron emission tomography/computed tomography revealed a mediastinal tumor measuring 3 × 5 × 6 mm located anterolateral to the aortopulmonary window. Minimally invasive removal of PA was performed through 3.5-cm reverse J-shaped partial upper sternotomy to the third intercostal space. Postoperative recovery was uneventful, and serum calcium and parathyroid hormone levels normalized within 24 hours of surgery. Our case represents the rare occurrence of a mediastinal PA associated with aberrant right subclavian artery treated with targeted minimally invasive approach using different imaging modalities including technetium-99m–sestamibi scintigraphy and fluorine-18 18F-fluorocholine positron emission tomography/computed tomography, and intraoperative use of gamma probe for precise localization PA.

Sign in / Sign up

Export Citation Format

Share Document